At the heart of this story lies the relationship between resources, technologies and economies, which, under distinct circumstances, may give rise to a major economic transformation. This raises a number of important questions: What constitutes the implied primacy of economics? Why is the KBBE the...
CRC is an ideal system to study the continuum of phenotypic states along malignant transformation as it follows a stereotyped progression from normal to atypical to carcinoma that includes the formation of precancerous polyps4,5, which can subsequently give rise to CRCs. A number of the changes...
We tested the performance of SCASL on defining cell subpopulations with single-cell RNA-seq data of embryonic tissue development, tumor cells, and tumor-associated immune cells. Cell lineage differentiation is extremely important in physiological and disease development. However, owing to the intrinsic ...
We also demonstrate that the two H3F3A mutations give rise to GBMs in separate anatomic compartments, with differential regulation of transcription factors OLIG1, OLIG2, and FOXG1, possibly reflecting different cellular origins. Graphical Abstract Download: Download high-res image (489KB) Download...
A recent study of double-strand repair mechanisms in yeast showed that those breaks that give rise to chromosome aberrations were repaired by homologous recombination (HR) between nonallelic Ty retrotransposons [42]. In light of the finding that HR between nonallelic repeat elements contributed to ...
Under steady-state conditions, stem cells in different regions of the epidermis only give rise to the differentiated cells appropriate for their location, but when the epidermis is damaged or genetically modified, individual stem cells exhibit a broader ability to differentiate into all epidermal ...
NTZ binds the CD49d receptor on the surface of leukocytes leading to the saturation of this receptor and changes in its expression. For this reason, the measurement of the saturation and expression levels of CD49d can give information about NTZ binding, which ultimately should impact the effecti...
metabolism (biology) the new replaces the old (idiom) Example Usage 新兴 Trad. 新興 xīn xīng new up-and-coming newly developing rising Show Strokes 摇身一变 Trad. 搖身一變 yáo shēn yī biàn to change shape in a single shake fig. to take on a new lease of life Example ...
Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy Introduction The phenotypic and functional differences between cells that initiate human breast tumors (cancer stem cells) and those that comprise the tumo... CM...
CRC is an ideal system to study the continuum of phenotypic states along malignant transformation as it follows a stereotyped progression from normal to atypical to carcinoma that includes the formation of precancerous polyps4,5, which can subsequently give rise to CRCs. A number of the changes...