Therefore, in this work, we evaluated the changes of energy metabolism in mononuclear cells (MNC) isolated from peripheral blood (PB), obtained from healthy population with an age between 5 and 106 years, analysing the oxidative phosphorylation (OXPHOS) function and efficiency, the ATP/AMP ratio,...
We have therefore employed the immortalized human T cell line Jurkat and somatic mutants derived from this cell line as tools for genetic studies of NK cell-receptor signaling pathways.These keywords were added by machine and not by the authors. This process is experimental and the keywords may ...
Postsynaptic density (PSD) proteins have been implicated in the pathophysiology of neurodevelopmental and psychiatric disorders. Here, we present detailed clinical and genetic data for 20 patients with likely gene-disrupting mutations inTANC2—whose protein product interacts with multiple PSD proteins. Pedi...
Inbred laboratory strains of mice are broadly organized into two groups, classical and wild-derived strains1, that can be used to model the variation observed in human populations2,3. Inbred laboratory strains of wild-derived origin represent a rich source of phenotypic responses and genetic diversi...
The features in this subset were considered as optimal features, and a corresponding optimal classifier was built on these optimal features. 2.3. Support Vector Machine SVM [24] is a widely used supervised-learning algorithm based on the statistical learning theory, which is applied to handle many...