- 《Microbiology & Molecular Biology Reviews》 被引量: 429发表: 2006年 The sites of cellulose synthesis in algae: Diversity and evolution of cellulose-synthesizing enzyme complexes that the architecture of cellulose microfibrils (size, shape, crystallinity, and intramicrofibrillar associations) is ...
Different requirements for EDS1 and NDR1 by disease resistance genes define at least two R gene-mediated signaling pathways in Arabidopsis The Arabidopsis genes EDS1 and NDR1 were shown previously by mutational analysis to encode essential components of race-specific disease resistance. Here, ... ...
Three traits were significantly associated with rare variant burden in thePRLRgene (n = 6 missense rare variants, β (se) = −1.17 (0.2),P = 1.2 × 10−8; Fig.3c). The most interesting among these included asymmetries in the distribution of mitochondria in the perinuclear...
In recent years, gene inactivation in the mouse and other model systems has shed new light on the processes of inductive tissue interactions and morphogene... Maxime,Bouchard - 《Differentiation》 被引量: 118发表: 2004年 Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and ...
The establishment of transcriptional silencing in yeast requires cell-cycle progression, but the nature of this requirement is unknown. Sir2 is a protein deacetylase that is required for gene silencing in yeast. We have used temperature-sensitive alleles of the SIR2 gene to assess Sir2's contribu...
Genome-wide association study of serum magnesium in type 2 diabetes Lynette J. Oost Roderick C. Slieker Jeroen H. F. de Baaij Genes & Nutrition(2024) GBA1 as a risk gene for osteoporosis in the specific populations and its role in the development of Gaucher disease ...
To identify the crosstalk between gene expression and metabolism in response to cold, drought and salt stresses, digital gene expression (DGE) analysis was... X Shan,Y Li,Y Jiang,... - 《Plant Molecular Biology Reporter》 被引量: 55发表: 2013年 Root Osmotic Adjustment under Osmotic Stress ...
High-throughput phenotype assays are a cornerstone of systems biology as they allow direct measurements of mutations, genes, strains, or even different genera. High-throughput methods also require data analytic methods that reduce complex time-series data to a single numeric evaluation. Here, we pres...
For mammals, which generally appear to lack localized cytoplasmic determinants, this process is guided by a genetic program encoded in the DNA of the zygote.doi:10.1385/1-59259-241-4:269S S PotterM T ValeriusE W BrunskillMethods Mol BiolMethods in Molecular Biology...
We hypothesize that tubulin-gene mutations may lead to intrinsic protein misfolding, causing disorders associated with dysregulated neurogenesis and degeneration of previously differentiated neurons. Landers and Shaw described eight TUBA4A variants in ALS patients and presented data suggesting that these ...