Through detailed kinetic studies, the polymerization proved to follow first order kinetics indicating a living/well-controlled reaction. The rate of polymerization depended on the size of the pendant groups in the cyclobutene rings, decreasing as the pendant group size increased. The living nature was...
For a zero order reaction, The rate becomes double when the order of the reaction. View Solution Define the term 'order of reaction' for chemical reactions. View Solution Exams IIT JEE NEET UP Board Bihar Board CBSE Free Textbook Solutions ...
First, HUVECs were found to have higher fluidity than MSCs (blue cells in Fig. 3A). Although the frequency and position of the first peak in the GP histogram (GP > 0.3) were comparable between MSCs and HUVECs (Additional file 1: Fig. S3), the frequency at the second peak of ...
Applicability domain can most readily be defined using chemical structure, properties and/or similarity; such approaches are often applied as a first step as these criteria lend themselves to being quantified easily. Other criteria are associated with the presence or absence of one or more structural...
and roasted coffee (750 mL in three servings every day for four weeks) showed increased activity of the Nrf2 pathway, which was defined by a significant increase in Nrf2 gene transcription in 36% of participants after four weeks of coffee consumption, in comparison to the first wash out ...
“plasma concentration-time curve”, extraction ratio.Half-lifeThe time taken for the plasma concentration of a drug to fall by 50% when first-order kinetics are observedMany drugs have an initial redistribution phase with a short half-life (t1/2α) followed by an elimination phase with a ...
Next, using a computational algorithm to interrogate the expression kinetics of a subset of genes profiled first at high resolution in differentiating PSCs, we select a set of optimal time points for global transcriptomic profiling and for these perform scRNA-seq time series analyses of PSC-...
In general, the time required to merge two filaments is the sum of the time for the two filaments to find each other and form their first crosslink, plus a time required to complete their merging. Direct measurements15 indicate that the latter timescale is of the order of a few hundred ...
TSG101 and HD-PTP show similar undulating kinetics. Based on our findings with the clathrin-binding mutant of HRS, we suggest that the first phase comprises both cargo sorting and membrane deformation. Phase 2: ESCRT-III and VPS4A show a rapid accumulation which may reflect polymerization of ...
It is clear that we did careful searching at this stage to find a better feature subset, which may not be tested in the first stage. Similarly, the SVM was executed on cells that were represented by features in each of these feature subsets, also evaluated by ten-fold cross-validation. ...