Dynamic Simulation allows you to define an exact location, called a Reference Frame, from which the Output Grapher expresses its results. Reference Frames are defined by an origin point and X and Y axes. Refere
Receptor-activated SMADs trimerize with SMAD4 to regulate context-dependent target gene expression. However, the presence of a single SMAD1/5/8 binding motif in cis-regulatory elements alone does not trigger transcription in native contexts. We hypothesi
The morphology of cells is dynamic and mediated by genetic and environmental factors. Characterizing how genetic variation impacts cell morphology can provide an important link between disease association and cellular function. Here, we combine genomic sequencing and high-content imaging approaches on iPSC...
In the current study we investigate TUBA4A, a structural microtubule protein with mutations causal to familial ALS, using molecular-dynamic (MD) modeling of protein structure to predict the effects of each mutation and its overall impact on GTP binding, chain stability, tubulin assembly, and ...
This misplaced accountability often happens because all stakeholders incorrectly view security as a technical or absolute problem to be solved, rather than a dynamic ongoing risk like corporate espionage and other traditional criminal activities.During this time of transformation, leadership of all teams ...
I propose a roadmap toward a conceptual framework and knowledge base of cell types that will enable a deeper understanding of the dynamic changes of cellular function under healthy and diseased conditions. Previous article in issue Next article in issue Introduction A cell is the basic unit of ...
The long 60 to 100-yr rotation periods make process-based modeling a powerful tool to evaluate the ecosystem services provided by boreal forests differing in age, species distribution, and management. Most ecological growth and yield models developed for boreal forests, however, focus mainly on wood...
This arrhythmogenic activity resulted in large error associated with FPD measurements which were removed from the graphical representation for the sake of clarity (Fig. 5f), but clearly a pharmaco- dynamic effect was detectable. In addition, cell viability in either the heart or liver chambers ...
I also meet the dynamic module does not define init function (init_caffe) during import caffe in python. Are you fix this problem now? Thanks! BRs, lnsyyj commented May 16, 2019 • edited I also encountered the same problem. /data/VOC0712/create_data.sh python changed to python3 ...
“Methods”) and scored all cells in the dataset by expression of this signature. This revealed a kinetically dynamic IFN response that peaked in all animals at 1 week post-infection but stayed persistently elevated in 170-infected animals relative to CL8-infected animals (Fig.2A). Additionally...