It is so interesting how math and science can sometimes go hand-in-hand. When it comes to research or experimentation, it is important to have mathematical concepts to explain how the process occurred. Answer and Explanation: A quantitative variable is a quantity that is described using numerical...
mlxtend 0.20.063, and xgboost 1.6.164. Instead of using a simple one-shot feature selection technique that usually yields a sub-optimal solution, we used a two-step feature selection process that generates
Genome-wide expression profiling identified five biological BC subtypes36, namely luminal A/B, HER2-enriched, basal-like and normal breast-like, which differ by hormonal receptor status, proliferation, genomic instability, mutational signatures, treatment response and prognosis37,38,39,40,41. It has...
... The stochastic model is simply the error in our ability to predict the outcome (dependent variable) for a particular input.Introduction to Deterministic Models42 related questions found What is the difference between deterministic and probabilistic models? A deterministic model does not include ...
Together our data indicate that clade-dependent polymorphismin the VPR84 and VPR85 residues defines the transducing properties mediated bythe C-terminal domain of HIV-1 VPR. Identification of this VPR polymorphismsuggests new approaches to understand the HIV-1 biology and/or pathogenesis. 展开 关键...
F Gaskin,CR Cantor,ML Shelanski - 《Journal of Molecular Biology》 被引量: 915发表: 1974年 The 2.2 Å crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with RaplA and a GTP analogue The X-ray crystal structure of the complex between the Ras...
The computational framework described here has multiple practical applications to the wider stem cell biology community and is accessible through open source code and web visualization engines detailed in the STAR Methods. Thus, our approach can be immediately applied for the analysis of scRNA-seq ...
High-throughput techniques have been used to analyze the global genome and transcriptome profiles of meningiomas with interesting insights into the biology of meningiomas [11–15]. However, these studies have either surveyed limited number of genes [14, 15], analyzed limited number of samples [11]...
Department of Biochemistry & Molecular Biology, Michigan State University, East Lansing, MI, USA Daniel C. Ducat Corresponding author Correspondence to Daniel C. Ducat. Additional file Additional file 1: Contains supplementary figures S1-S15 as well as the mathematical framework used to investigate mic...
Male reproductive system ageing is closely associated with deficiency in testosterone production due to loss of functional Leydig cells, which are differentiated from stem Leydig cells (SLCs). However, the relationship between SLC differentiation and age