Let’s summarize. In physics, the word information is closely related to microstates and probabilities. In some limited circumstances information is equal to entropy, but in most cases not. Information should never be confused with knowledge despite what natural language and the dictionary say. And ...
In this paper we discuss some ideas on how to define the concept of quasi-integrability. Our ideas stem from the observation that many field theory models are "almost" integrable; i.e. they possess a large number of "almost" conserved quantities. Most of our discussion will involve a ...
Several genes have hotspots at conserved sites and are poorly presented (Fig. 1e), implying that the fitness advantages the mutations confer may be driven by both features. We focused on TP53 because it is widely mutated in tumours, with well-established, order-conserved pan-cancer hotspots (...
Functional studies showed that the R320C α-tubulin mutant, after transient overexpression in HEK293 cells, was particularly defective in generating α/β tubulin dimers4. The R320 residue of TUBA4A is conserved from metazoa to humans, implying that it plays a critical role in determining the str...