D. STARR-seq and UMI-STARR-seq: assessing enhancer activities for genome-wide-, high-, and low-complexity candidate libraries. Curr. Protoc. Mol. Biol. 128, e105 (2019). Article PubMed Google Scholar Mahat, D. B. et al. Base-pair-resolution genome-wide mapping of active RNA ...
The intestinal epithelium, with its complex array of cell types, plays a fundamental role in recognizing microbes and shaping downstream immune responses. Moreover, although it is clear intestinal epithelial cells are essential players, we are only beginning to unravel the immune mechanisms involved. ...
To specify that inputs are constants, use the-argscommand-line option with acoder.Constantobject. To specify that an input is a constant with the size, class, complexity, and value ofconstant_input, use the following syntax: -args {coder.Constant(constant_input)} Calling Functions with Consta...
Studies over the past century have revealed that cells within an organism can be grouped into types—cells within a type exhibit similar structure and function that are distinct from cells in other types (Arendt, 2008). Categorizing cells into types greatly reduces the complexity of investigating ...
Minimize the complexity of your dependencies. Prefer simpler frameworks that load quickly on execution environment startup. Minimize your deployment package size to its runtime necessities. This will reduce the amount of time that it takes for your deployment package to be downloaded and unpacked ah...
Minimize the complexity of your dependencies.Prefer simpler frameworks that load quickly onexecution environmentstartup. Minimize your deployment package size to its runtime necessities.This will reduce the amount of time that it takes for your deployment package to be downloaded and unpacked ahead of...
Use a JSON schema to define the configuration of your Splunk SOAR app. The JSON may vary in complexity depending on the sophistication of the app and whether you want to customize how data produced by your app is rendered. Top level definition ...
In Alzheimer’s disease (AD), microglia form distinct cellular aggregates that play critical roles in disease progression, including Aβ plaque-associated microglia (PaM) and the newly identified coffin-like microglia (CoM). PaM are closely associated with amyloid-β (Aβ) plaques, while CoM are...
Each algorithm has its own type of convergence, time to get a solution, complexity and accuracy. Thankfully, many spreadsheet programs have powerful and flexible optimization functions available. Typically, Excel uses a generalized reduced gradient (GRG2) non-li...
Defining the domain using toxicodynamics or toxicokinetics is associated with a higher level of complexity and it is generally more difficult to assign chemicals to a domain using this type of information, particularly where qualitative descriptions are given, such as “rapid” absorption. Thus, it ...