Current thresholds to define chronic kidney disease (CKD) are essentially based on two measures, estimated GFR (eGFR) and albuminuria. The first two stages (stage 1 and 2) are mainly defined by the presence of abnormal albuminuria (>30 mg/g creatinine). Conversely, overt CKD (stages 3-5)...
Modrall et al have reanalyzed data from the CORAL trial2 to identify a role for renal artery stenting (RAS) in the subset of patients with chronic kidney disease (CKD). They demonstrated, again, that stenting does not provide a benefit compared with optimal medical therapy in terms of event...
Mosaic loss of Y chromosome is associated with aging and epithelial injury in chronic kidney disease Parker C. Wilson Amit Verma Benjamin D. Humphreys Genome Biology(2024) Associated content Linking genetic variants to kidney disease via the epigenome ...
including analyses of samples from urogenital diseases (kidney transplantation [8], diabetic nephropathy [9], obstructive nephropathy [10], bladder cancer [11], prostate cancer [12], and others) and non-urogenital diseases (hematopoietic stem cell transplantation [13], coronary artery disease [14]...
Cardiovascular complications, including stroke, may be attributed the highest rate of morbidity and mortality in patients with chronic kidney disease (CKD). The aim of our study was to evaluate the prevalence of CKD in patients with symptomatic ischaemic cerebrovascular disease and to establish of ...
measures to define chronic kidney disease—reply:developing guidelines for chronic kidney disease: we should include all of the outcomes.in reply: the nuances raised by dr o'hare are important but they do not invalidate our interpretation that "although some variation in management of ckd should ...
chronic kidney diseaseelderlyestimated glomerular filtration rateyoungThe conventional definition of chronic kidney disease (CKD) primarily relies on the identification of albuminuria or a decline in estimated glomerular filtration rate (eGFR). For many years, a straightforward eGFR threshold of <60ml/min...
There was poor agreement between conventional and KDOQI definitions of anemia in children with CKD.doi:10.1007/s00467-006-0397-7Guido FillerKyle MylreaJanusz FeberHubert WongspPediatric NephrologyFiller G, Mylrea K, Feber J, Wong H. How to define anemia in children with chronic kidney disease?
Correction of metabolic acidosis is an important goal in the management of patients with chronic kidney disease (CKD). However, there is no consensus as to what constitutes an optimal correction of metabolic acidosis in this setting – various expert groups from around the world have set different...
Introduction: Due to a lack of spatial-temporal resolution at the single cell level, the etiologies of the bone dysfunction caused by diseases such as normal aging, osteoporosis, and the metabolic bone disease associated with chronic kidney disease (CKD) remain largely unknown...