Channels: DAPI staining excitation 405nm, emission 450/50nm, exposure 100ms; CD55 staining excitation 488nm, emission 495/20nm, exposure 200ms; COL1A1 mRNA staining excitation 561nm, emission 620/60nm, exposure
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene have been recognized as genetic risk factors for Parkinson’s disease (PD). However, compared to cancer, fewer genetic mutations contribute to the cause of PD, propelling the search for protein b
In total, we determined a panel of unique proteins and phosphoproteins as novel high-confidence candidates for disease biomarkers. Disease biomarkers will help diagnose whether a patient currently has PD. Our large-scale LC-MS analysis efforts combined with extensive bioinformatics analysis led to the...
Quantification of size distributions of vesicles from TEM for each filter fraction and UC (100,000 × g) reveals a separation of vesicles accordingly (Figure 1F). Together, these results validate the filtration protocol approach for effectively separating vesicles by subtypes from mouse primary GBM ...