Ionized calcium-binding adaptor molecule 1 IHC: Immunohistochemistry IRM: Interferon response microglia ISH: In situ hybridization ITGA6: Integrin subunit alpha 6 KEGG: Kyoto Encyclopedia of Genes and Geno
Thrombin generation can also be triggered by exposure of the blood to the artificial surface of the valve leaflets and sewing ring, which induces activation of the contact pathway of coagulation before endothelialization has occurred. Whereas dabigatran exclusively inhibits thrombin, VKAs are likely to ...
led to a frameshift and the introduction of a premature stop codon after residue E1091. WT and mutant EGFR proteins were expressed at similar levels, but the migration of the mutant EGFR was consistent with a smaller protein lacking C-terminal epitopes and phospho-epitopes (Fig.6c). MAPK sign...
respectively (Extended Data Fig.1d). Compared to other benign ductal cells, LM cells expressed high levels ofERBB4,DACH1 and ESR1, with hormone-response pathways enriched among differentially expressed genes (Fig.2band Supplementary
et al. Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation. Cell 59, 33–43 (1989). Article CAS PubMed Google Scholar Lovly, C. et al. Detection of diverse EGFR C-terminal truncations (C-trunc) and...
To compare functional properties among transcriptomic cell types, two general approaches have been taken—coupling in vivo calcium imaging with post hoc multiplexed FISH to decode the molecular identities of the imaged cells (Bugeon et al., 2022; Condylis et al., 2022; Lovett-Barron et al., ...
Describe the role of calcium ions (Ca2+ ions) in muscle contraction. Describe the structure of a cholinergic synapse, and explain how it functions. Describe the secretions of the various cells in the stomach and the functions of their secretions. What is the cytoskeleton? what does it do? D...
In general terms, how could changing calcium ion levels within a cell affect the function of certain proteins? Explain the structural classification of hormones. Explain how the different structural classifications of hormones are able to interact with their target cells...
A. Secondary processing of the Plasmodium falciparum merozoite surface protein-1 (MSP1) by a calcium-dependent membrane-bound serine protease: shedding of MSP133 as a noncovalently associated complex with other fragments of the MSP1. Mol. Biochem. Parasitol. 50, 307–315 (1992). Article CAS ...
The biochemical analyses were performed on mononuclear cells isolated from peripheral blood, obtained from a healthy population with an age between 5 and 106 years. In particular, we have evaluated the oxidative phosphorylation function and efficiency, the ATP/AMP ratio, the lactate dehydrogenase ...