These additional perturbed sites may indicate a secondary point of interaction with XcpJp, or changes in XcpHp propagated through its structure after binding to XcpJp. Global smaller amplitude changes across much of XcpHp suggest that the XcpHp:Jp interaction subtly affects the dynamics or the ...
WIZ/CTCF peaks showed decreased nucleosome occupancy, while WIZ peaks not overlapping CTCF peaks tend to be of low-amplitude signal and do not show well-positioned nucleosomes (Figure S2B) (Mullen et al., 2011). Taken together with the coIP experiments, our data suggest that WIZ exists in ...