Comparing the results of all approaches similar number of mismatches were observed.For both HLA class I and class II, we found that increasing numbers of AA mismatches resulted in a higher probability of DSA formation (as indicated in figure 1).This newly developed computer algorithm ...
Using full length genomic DNA next generation sequencing (NGS) for actual recipient and donor pairs, and sera known to contain DSA by single antigen beads (SAB), we developed a novel computer algorithm to define the exact regions being recognized, unbiased with respect to locus or position in ...