Male reproductive system ageing is closely associated with deficiency in testosterone production due to loss of functional Leydig cells, which are differentiated from stem Leydig cells (SLCs). However, the relationship between SLC differentiation and age
Furthermore, the emerging system/network analysis has revolutionized novel mechanism discovery and promising drug targets. Our literature-based network analysis of the gene expression involving these potential biomarkers has revealed the connections between our biomarkers and critical pathways that could lead ...
NSCLC cells, the secretion of IGF and IGF-binding proteins (IGFBPs) was linked to the drug sensitization of EGFR-TKI [196]. As mentioned, deleting αSMA+myCAFs in PDAC increases immunosuppression and reduces OS. A previous study has reported that CAFs can impede PDAC progression by hypoxia. ...