The study identified 120 patients (number of biopsies per assay detailed in Figure S1A) treated with anti-PD-1 monotherapy (nivolumab or pembrolizumab; n = 63 patients) or combined anti-CTLA-4 and anti-PD-1 therapy (nivolumab or pembrolizumab combined with ipilimumab; n = 57 patients). Pati...
The revealed features delineate a taxonomy of N-linked glycan-glycan interactions. Crowded and dispersed glycans are differently ordered, conserved, processed, and recognized by antibody. The structures, along with glycan-array binding and molecular dynamics, reveal a diversity in oligosaccharide affinity...
the urine volume was normalized based on the creatinine levels, a normalizer we found to be optimal for EV studies. The EVtrap beads were provided by Tymora Analytical Operations and were utilized and validated as described previously26,27,28,37,39. In brief,...
在使用UIAbilityContext时报401“The context must be a valid Context”的Context类型错误 应用、元服务和卡片是什么关系 系统应用、三方应用、预置应用有什么差别 如何设置默认语言和应用名称为中文 如何查询应用进程的pid信息 有了代码签名特性后,开发者的so文件在调试,发布等阶段该如何部署 app.json5文件与...
HAP依赖HAR A,HAR A依赖HAR B,HAP能否调用HAR B提供的接口?如果不支持间接依赖HAR,这么设计的原因是什么? 通过resourceManager.getStringResource接口获取HSP资源文件报“Resource id invalid”错误 HAP/HAR/HSP的关系是什么?是否都可以声明注册Ability和Page?三种类型分别推荐哪些的使用场景?选择原则是什么 如何正确...
The leader/first spacer region of CRISPR7 was amplified with primers and a serial PCR protocol indicated in Figure 1D. Asterisks indicate the PCR product corresponding to the parental array with no new spacer, and the product corresponding to the array with a new repeat-spacer unit is ...