2. Relative charge: The composition of amino acids may affects the charge of the protein. 3. Post-translational modification: Phosphorylation, glycosylation, methylation etc. 4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleaved ...
The level of HA-p53 was then analyzed at 6 hpi. Dele- tion of the first 189 (construct D1) or 377 (construct D2) amino acids (AAs) from the N-terminus, which contains the NoLS, almost totally abolished the ability of Def to promote HA-p53 degradation. In contrast, deletion of the...
DEF6 Antibody 应用类型 WB 免疫原 Recombinant fusion protein containing a sequence corresponding to amino acids 60-330 of human DEF6 (NP_071330.3). 来源宿主 兔 反应性 人, 小鼠, 大鼠 保存建议 Store at -20˚C. Avoid freeze / thaw cycles. 其他 ProSci Incorporated于1998年成立于美国加州圣地亚...
2. Relative charge: The composition of amino acids may affects the charge of the protein.3. Post-translational modification: Phosphorylation, glycosylation, methylation etc.4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleavedto give the active form.5. ...
Recombinant fusion protein containing a sequence corresponding to amino acids 1-76 of human DEFB121 (NP_001011878.1). 来源宿主 rabbit 反应性 human,mouse,rat 保存建议 -20 其他 Nordic BioSite(北欧生物) 总部位于瑞典,成立于1997年,旨在分销研究和诊断领域的高质量和创新产品。 Nordic BioSite 被公认为整个...
In this report, by using a series of truncated or internally deleted human CAPN3 (hCAPN3) derivatives we identify that an essential motif of 86 amino acids (86-aa) (430-515aa) in hCAPN3 for its interaction with human Def (hDef), and this 86-aa motif is highly conserved in zebrafish...
(DEF) is a component of the SSU processome in the nucleolus and is evolutionarily conserved from yeast (named UTP25) to humans (33% identical and 50% similar at the amino acid level, https:// blast.ncbi.nlm.nih.gov/).6–8 In the zebrafish, we have previously shown that Def is ...
The full length def transcript is of 5,570 bp in length and the def open reading frame (ORF) encodes a peptide of 768 amino acids (aa). In order to study the mouse def function, we generated a transgenic mouse line (deffrt*loxp) by replacing the exon3 plus flanking intron-2 and...
antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. The mature form of Beta defensin 1 is 36 amino acids. ...
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