Motif co-occurrence uncovers the regulatory rules of gene expression To determine the functional meaning of the DNA motifs reconstructed from the deep learningrelevanceprofiles (Fig.3f), we analysed the informative power of the DNA motifs for predicting the specific gene expression levels. For this,...
Deep learning has been applied and shown great performance in modelling chemical spaces18, gene expression19, enzyme-related parameters such as enzyme affinity20and EC numbers21. Previously, Heckmann and colleagues employed machine learning approaches to predictE. coli kcatvalues based on features such...
Deep Learning for Regulatory Genomics - Regulator binding, Transcription Factors TFs(调节基因组学的深度学习:调节器结合、转录因子TFs) Gene Expression Prediction(基因表达预测) Single Cell Genomics(单细胞基因组学) Dimensionality Reduction(降维) Disease Circuitry Dissection GWAS(疾病电路解剖GWAS) GWAS mechanism...
Regulatory Genomics - Deep Learning in Life Sciences(调节基因组学) Deep Learning for Regulatory Genomics - Regulator binding, Transcription Factors TFs(调节基因组学的深度学习:调节器结合、转录因子TFs) Gene Expression Prediction(基因表达预测) Single Cell Genomics(单细胞基因组学) Dimensionality Reduction(降...
Deep Learning for Regulatory Genomics - Regulator binding, Transcription Factors TFs(调节基因组学的深度学习:调节器结合、转录因子TFs) Gene Expression Prediction(基因表达预测) Single Cell Genomics(单细胞基因组学) Dimensionality Reduction(降维) Disease Circuitry Dissection GWAS(疾病电路解剖GWAS) ...
注意,这些数据集在示例数量和可能的标签数量上相对比较少。 参考文献 [1]. A Keras implementation of the DeepMIMLNetwork for multi-instance multi-label learning. https://github.com/kingfengji/DeepMIML [2]. JiFeng, Zhi-Hua Zhou:Deep MIML Network. AAAI 2017: 1884-1890...
deep learningautoencodermultilayer perceptronIn the field of molecular biology, gene expression is a term that encompasses all the information contained in an organism's genome. Although, researchers have developed several clinical techniques to quantitatively measure the expressions of genes of an ...
Enhancing the prediction of disease-gene associations with multimodal deep learning. 来自 NCBI 喜欢 0 阅读量: 102 作者:Ping,Luo,Yuanyuan,Li-Ping,Tian,Fang-Xiang 摘要: Computationally predicting disease genes helps scientists optimize the in-depth experimental validation and accelerates the identification...
DeepProg: an ensemble of deep-learning and machine-learning models for prognosis prediction using multi-omics data DeepProg:使用多组学数据的预后预测的深度学习和机器学习模型集成 01 文献速递介绍 大多数基于生存的分子签名都是基于单一类型的组学数据[1]。由于每种组学平台都有其特定的局限性和噪音,基于多组...
Deep learning methods for digital pathology analysis are an effective way to address multiple clinical questions, from diagnosis to prediction of treatment outcomes. These methods have also been used to predict gene mutations from pathology images, but no comprehensive evaluation of their potential for ...