The search for effective drugs that induce cancer death and inhibit the death of immune cells and normal tissue cells is a promising direction for future cancer therapy. Open Questions Which structural elements contribute to the dual role of Tspan protein family members in cancer development and pro...
The pathogenesis of Acute-on-chronic liver failure (ACLF) involves several forms of cell death, such as pyroptosis, apoptosis, and necroptosis, which consist of PANoptosis. To explore PANoptosis as a regulated cell death pathway in ACLF. Firstly, a bioin
Cause-Specific Mortality: Skin and Soft Tissue Infections eTable 17. Findings From Observational Studies on the Pooled Cause-Specific Mortality Rates, and Mortality Rate Ratios in People Receiving OAT, by Specific Time Periods In and Out of Treatment eFigure 25. Studies on the Association of ...
All organisms end with their death, and many parts of cells die through intrinsic suicide machineries in response to diverse stimuli. These intrinsic cell death pathways are often termed as programmed cell deaths (PCDs), and are critical for organism development, tissue homeostasis and various disea...
Utilization of intravenous tissue plasminogen activator for ischemic stroke: are there sex differences? Cerebrovasc Dis. 2009;27(3):254-258.PubMedGoogle ScholarCrossref 33. Saver JL, Fonarow GC, Smith EE, et al. Time to treatment with intravenous tissue plasminogen activator and outcome from ...
MicroRNA: A matter of life or death Zhiguo Wang Zhiguo Wang, Research Center, Montreal Heart Institute and Department of Medicine, University of Montreal, Montreal, PQ H1T 1C8, Canada Author contributions: Wang Z solely contributed to this paper. Correspondence to: Zhiguo Wang, PhD, FAHA,...
During the spring of 2009, a pandemic influenza A (H1N1) virus emerged and spread globally. We describe the clinical characteristics and factors associated with the death of patients who were hospitalized with 2009 H1N1 influenza pneumonia in Shenyang, C
The aim of this paper is to use the novel lace plant system to delineate the possible order of organelle changes that occur throughout developmental PCD using both in vivo long- and short-term live cell imaging. This study will also employ experiments using fixed tissue samples in order to ...
mechanism involves NK cells inducing apoptosis in TRAIL-R2 expressing T cells Mediated by caspase-8. This selective elimination of specific T-cell subsets, rather than promoting inflammation, may aid in establishing immune tolerance, preventing excessive immune responses, and maintaining tissue homeostasis...
Preclinical models of CTCs CTC-derived xenografts Patient-derived xenografts (PDXs), established by engrafting pieces of human tumor tissue into immunocompromised mice, represent a very useful preclinical model for more faithful disease modeling and a step towards precision medicine. Obtaining biopsy mater...