Necrosis is a type of cell death characterized by a gain in cell volume, swelling of organelles, rupture of the plasma membrane and subsequent loss of intracellular contents. For a long time, the process has been considered as a merely accidental and uncontrolled form of cell death, but accumu...
In addition, ERs-induced apoptosis is particularly important in the progression of NAFLD, as many drugs have been found to reduce the occurrence of apoptosis in hepatocytes by inhibiting ERs. Tanshinone IIA (Tan IIA) significantly inhibited the expression of ERK-related molecules GRP78, ATF6, and...
In addition, ERs-induced apoptosis is particularly important in the progression of NAFLD, as many drugs have been found to reduce the occurrence of apoptosis in hepatocytes by inhibiting ERs. Tanshinone IIA (Tan IIA) significantly inhibited the expression of ERK-related molecules GRP78, ATF6, and...
A sexual dimorphism at the cellular level has been suggested to play a role in cancer onset and progression. In particular, very recent studies have unraveled striking differences between cells carrying XX or XY chromosomes in terms of response to stressful stimuli, indicating the presence of geneti...
Wilson DM, Cohen J, Deliens L, Hewitt JA, Houttekier D. The preferred place of last days: results of a representative population-based public survey. J Palliat Med. 2013;16(5):502–8. https://doi.org/10.1089/jpm.2012.0262. Article PubMed Google Scholar Yamagishi A, Morita T, Miyashi...
Brain death, also commonly referred to as death by neurologic criteria, has been considered a legal definition of death for decades. Its determination involves many considerations and subtleties. In this review, we discuss the philosophy and history of b
Role of the battalion surgeon in the Iraq and Afghanistan war Theattalionurgeon isn invaluablesseto deployingnit.he primaryolefattalionurgeon iso provideasic primaryareedicinendombatesuscitation.ther expectations incl... Moawad,J F.,Wilson,... - 《Military Medicine Official Journal of Amsus the...
such as redox reactions and the mitochondrial respiratory chain. Disturbances in copper ion metabolism leads to the well-known Wilson’s disease [204], on the other hand, depletion of copper ions in mitochondria is associated with tumor suppression [205]. Ferroptosis is another trace element-depend...
Objective: The aim of this study was to determine the association between chronic placental inflammation and amniotic fluid (AF) markers of maternal anti-fetal rejection as well as the presence of microorganisms in the AF fluid of patients with fetal dea
Wilson's disease is due to ATP7B gene mutation leading to copper transport dysfunction or abnormal protein transport, resulting in abnormal accumulation of copper in certain tissues (Marreiro2017; McAlary et al.2022). Moreover, copper imbalance has been implicated in the mechanism of pathogenesis ...