I was once the Production Manager in a small aerospace instrumentation firm with a Chief Engineer whose only claim to fame as far as I could tell, was his ability to make everything he was involved with seem much more complex than it was. I once went to chat with him about a specialize...
There are a few things about how Anne died we can claim with confidence. She did not die in hospital, because Georges chose to keep his promise to her and never let her return there. She did not die as the result of a grisly and natural deterioration, because Georges chose to abandon ...
We claim that silencing of PERK during ER stress increases cell viability. We also show that the apoptotic cell death induced by IRE-1-activated JNK is abrogated in the siPERK cell line assuming a positive feedback loop between the PERK and IRE-1 arms of UPR. Our mathematical model reveals...