neuroplastin plasma membrane calcium ATPase mutation cytosolic calcium regulation Abbreviations Nptn neuroplastin (Np) gene PMCA of plasma membrane calcium (Ca2+) ATPases WT wild-type The mammalian auditory system perceives sensory input in the ear and transforms it into electrical impulses by mechan...
Contact Dermatitis of the Ear In some dogs, the inner, hairless side of the pinna can become inflamed and irritated after the application of certain ointments or medications. This inflammation, calledcontact dermatitis, can develop 1–7 days after starting a treatment. The skin of the pinna can...
Functional effects of the mutations were tested through in vitro analysis. The p.Phe111Val, p.Trp142Arg, p.Ser431Argfs*71, and p.Arg433Gln alterations were tested with a construction allowing production of SOX10 with a Myc tag at its amino terminus. After confirmation of the protein ...
Msrb3 is expressed widely. In the inner ear, it is found in the sensory epithelium of the organ of Corti and vestibular end organs as well as in cells of the spiral ganglion. Taken together, MSRB3-catalyzed reduction of methionine sulfoxides to methionine is essential for hearing....