mRNAs that accumulate after ALPH1 RNAi are deadenylated.Susanne, Kramer
Uridylation is a widespread modification destabilizing eukaryotic mRNAs. Yet, molecular mechanisms underlying TUTase-mediated mRNA degradation remain mostly unresolved. Here, we report that the Arabidopsis TUTase URT1 participates in a molecular network connecting several translational repressors/decapping ac...
目前尚不清楚mRNAs是否在细胞质中发挥结构作用。 2024年8月5日,美国纪念斯隆-凯特琳研究所Christine Mayr团队在Cell在线发表题为“The FXR1 network acts as a signaling scaffold for actomyosin remodeling”的研究论文,该研究报道了脆性X相关蛋...
NSD degrades mRNAs lacking a stop codon, while NGD recognizes and decays mRNAs that contain translation elongation inhibitory structures. NGD has been intensively studied in yeast and animals but it has not been described in plants yet. In yeast, NGD is induced if the elongating ribosome is ...
Most interestingly, using binomial logistics models we found that a signature of six mRNAs (,,and) distinguished treatment-resistant from responsive patients, even after adjusting for other variables that were different between groups, such as a trait- and state-anxiety, history of childhood ...
Nonsense-Containing mRNAs That Accumulate in the Absence of a Functional Nonsense-Mediated mRNA Decay Pathway Are Destabilized Rapidly upon Its Restitution Belk, F. He, A. Jacobson, Nonsense-containing mRNAs that accumulate in the absence of a functional nonsense-mediated mRNA decay pathway are dest...
The presence of subgenomic mRNAs in virions of IBV was examined by probing Northern blots of RNA extracted from virions using as a probe a cDNA of the 3′-terminal nucleocapsid protein (N) gene. This detects all five mRNAs because of the 3′-coterminal, nested-set arrangement of coronavirus...
Different response to inflammation of the multiple mRNAs of rat N-acetylglucosaminyltransferase I with variable 5′-untranslated sequencesDifferent response to inflammation of the multiple mRNAs of rat N-acetylglucosaminyltransferase I with variable 5′-untranslated sequencesdoi:10.1016/s0014-5793(98)01...
Determination of Isozyme-Specific mRNAs of 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase in Glutamate Obese Rats by RNA Probes : Biological Chemistry Hoppe-SeylerDetermination of Isozyme-Specific mRNAs of 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase in Glutamate Obese Rats ...
Expression of myelin Po and PI mRNAs did not fall during EAN, nor rise during recovery. Fc γ mRNA, which encodes Fc γ RIII, an immunogloubulin-binding protein mediating activation of natural killer cells and macrophages by immune complexes, was transiently, but markedly induced in scattered ...