网络如蛋白质的从头折叠 网络释义 1. 如蛋白质的从头折叠 分子伴侣-食... ... α-螺旋( α-helix) 等。在细胞应急和非应急条件下的蛋白质代谢,如蛋白质的从头折叠(de novo protein fol… www.foodmate.net|基于16个网页
De novo protein structure determination from near-atomic-resolution cryo-EM maps We present a de novo model-building approach that combines predicted backbone conformations with side-chain fit to density to accurately assign sequence into density maps. This method yielded accurate models for six of ni...
Recently, for the first time that we know of, a small protein with an independent βαβ structure (DS119) was successfully designed in our laboratory. To understand the folding mechanism of DS119, in the study described here, we carried out all-atom molecular dynamics and coarse-grained ...
A de novo approach would be based almost entirely on general principles of energy and entropy that govern protein folding energetics, and importantly do so without the use of the amino acid sequences and structural features of other proteins. Most consider that problem as still unsolved even ...
学术范收录的Journal What has de novo protein design taught us about protein folding and biophysics,目前已有全文资源,进入学术范阅读全文,查看参考文献与引证文献,参与文献内容讨论。学术范是一个在线学术交流社区,收录论文、作者、研究机构等信息,是一个与小木
Thus, it is of great interest to investigate the folding mechanism of de novo designed proteins, which will be helpful in understanding protein folding mechanism and further improving protein design methods. Since systematic kinetic/thermodynamic studies of DS119 or similar proteins with parallel β-...
De novo synthesis and secretion of a 36-kD protein by cells that form lupus inclusions in response to alpha-interferon. In response to the pure recombinant human alpha-IFN, IFLrA, Raji and Daudi were the only two cell lines among 19 human lymphoblastoid cell lines tested tha......
Recently, for the first time that we know of, a small protein with an independent betaalphabeta structure (DS119) was successfully designed in our laboratory. To understand the folding mechanism of DS119, in the study described here, we carried out all-atom molecular dynamics and coarse-...
来源期刊 International Journal of Molecular Sciences 2012 研究点推荐 de novo Protein Folding 引用走势 2014 被引量:1 0关于我们 百度学术集成海量学术资源,融合人工智能、深度学习、大数据分析等技术,为科研工作者提供全面快捷的学术服务。在这里我们保持学习的态度,不忘初心,砥砺前行。了解更多>> 友情链接 ...