网络蛋白质全新设计;从头蛋白设计 网络释义
蛋白质设计的物理原则(Physical principles that underlie protein design) 蛋白质折叠的驱动力是将疏水残基从溶剂中埋藏到蛋白质的核心部位(三种学说之一),为了最小化蛋白质在溶剂中占据的空穴和最小化原子重叠的范德华力,蛋白质的侧链必须被紧密地包装且不溶于任何能量不利地重叠。在展开状态下与溶剂形成氢键的残基...
de novo protein 新的蛋白质 双语对照 例句:1.And such an inhibition might necessitate de novo protein synthesis.而这种抑制作用需要新的蛋白质合成。2.De novo synthesis of protein is essential for the complete regeneration of flagella.蛋白质重新合成对於鞭毛的再生是必须的 ...
首先是计算:从头蛋白质设计在计算上是昂贵的,而计算能力可用性的稳步增长极大地促进了我们描述的工作,其中大部分是通过Rosetta@home项目使用志愿者计算完成的。第二个进步是DNA的合成制造。由于正在设计的蛋白质在自然界中不存在,因此编码其氨基酸序列的基因也不存在。为了在生物体(如大肠杆菌)中生产设计的蛋白质,必须...
a来中国就有自己的电视了。 正在翻译,请等待...[translate] athe three kinds of patents have different effects 这三专利有不同的作用[translate] acertificate of advanced career english 先进的事业英语证明[translate] a线性回归方程 Equation of motion[translate] ade novo protein 新的蛋白质[translate]...
denovo是什么意思 网络从头; 从头合成; 从头合成途径 词组短语 1.DeNovostenting置入支架;植入支架 2.AllyDenovo瑞士超美型摩登手表 3.DenovoTumors新发肿瘤 4.denovopathway与新生途径 5.denovosynthesis[生化]全程合成 6.DenovoProtein Design全新蛋白质设计 ...
This suggest design model very close to true structure Top7 crystal like the model was also judged to be a novel topology by TOPS server Comparison of model (blue) and the solved x-ray structure (red) Implications Atomic Level Accuracy (RMSD = 1.17 oA) in de novo Protein Design ...
protein engineering as it could enable the construction of switchable nanomaterials, cooperatively activated biosensors and molecular machines that perform work by means of coordinated movements among their components. Previous work on the de novo design of allostery has demonstrated coupling between two ...
De novo protein design seeks to generate proteins with specified structural and/or functional properties, for example, making a binding interaction with a given target12, folding into a particular topology13or containing a catalytic site4. Denoising diffusion probabilistic models (DDPMs), a powerful ...