eThpehpyseiacka-ltosi-zaeveorfatgheepPoTwOersrtaruticotduerefinsoestthhaet vtholeupmeeakofmthoemenenertgcya-nstboeraegfefescytsivteemly trheasitsdteedli.vTehrsespmeaoko-tthoe-advpeorawgeerptoowtheer grartidio[d3e8fi,3n9e].sAthlesov,oalulamrgeeopf ethaek-etnoe-argvye-rsatgoerapgoewsyer...
Overall, the data suggest that deBouganin is effective against tumor cell resistance mechanisms selected in response to ADCs composed of anti-microtubule payloads. Keywords: immunotoxin; deBouganin; ribosome inactivating protein; HER2; C6.5 diabody 1. Introduction Antibody Drug Conjugates (ADCs) are...
Genetic fate-mapping studies suggest that this is the dominant mechanism for cardiomyocyte production in the adult mammalian heart [5,7,8,10]. However, the majority of studies estimate the rate of cardiomyocyte proliferation to be very low during adulthood, at or below ~1% per year [1,2,4...
[o3d2–e3ls6,].siInntceermtheedyiadteespcerrifboermaasnccaesttearriengprboevhidaevdiowr imthocroess im ainladr ctoosth e mSPodMelsm, osidnecle than the cothseϑymdeosdcreilb.eHa oscwatetevreinr,gthbeeheaxvpiolromitaotrieosnimoiflatrhteoathperSiPoMri smcoadtteelrtihnagnitnhfeorcmosati...