免疫细胞的分化主要由转录因子进行调控,DC-SCRIPT 是DC特异性高表达的转录因子【4】,主要表达在cDC及其祖细胞中,但不表达在pDC 中,并且在cDC1中高表达,但是DC-SCRIPT在DC中的作用还未知。DC-SCRIPT 对DC分化和功能的影响是本研究的核心...
DC-SCRIPT对于骨髓中前体cDC1祖细胞的特化是可有可无的,但在该谱系进一步成熟时,DC-SCRIPT对于维持足够水平的IRF8是必不可少的,从而证实了IRF8 +32kb增强子在控制cDC1成熟中的关键作用。 DC-SCRIPT如何调控Irf8 +32-kb增强子的活性,目前尚不清楚,但可能涉及该位点染色质可及性的变化,这是因为Batf3的表达本身在...
Interestingly, FGFR1, the dominant FGF2 receptor, was expressed at a significantly lower level in basal epithelial cells of DC-SCRIPT deficient organoids relative to wildtype organoids. A potential link between DC-SCRIPT and FGFR1 was further supported by the predicted locations of the DC-SCRIPT ...
Trans_DC_Script_20250109.zip Nom de versionON Toolkit Plugin&Script 23.016 Nom du logicielTrans_DC_Script_20250109.zip Date de sortie2025-01-10 Taille906.27MB Description TélechargerTélécharg By downloading a software package, you agree toHuawei Enterprise Software License Agreement....
Trans_DC_Script_20250123.zip Nom de versionON Toolkit Plugin&Script 23.017 Nom du logicielTrans_DC_Script_20250123.zip Date de sortie2025-01-24 Taille911.26MB Description TélechargerTélécharg By downloading a software package, you agree toHuawei Enterprise Software License Agreement....
Abstract. Dendritic cell-specific transcript (DC-SCRIPT) is a putative DC zinc (Zn) finger-type transcription factor described recently in humans. Here, we
DC-SCRIPT was identified in barramundi by homology using RACE PCR and genome walking. Specific expression of DC-SCRIPT was detected in barramundi cells by Stellaris mRNA FISH, in combination with MHCII expression when exposed to bacterial derived peptidoglycan, suggesting the presence of DCs in L....
dc-script-common / config.lua config.lua334 Bytes 一键复制编辑原始数据按行查看历史 Joshua提交于2个月前.init 1234567891011121314151617181920 SysConfig={ -- wifi or 4g network_type="wifi" } functionSysConfig:getNetworkType() returnself.network_type ...
The following script sets up CSV data connect in new book with sample CSV data and run script to add "Mean" label row to show mean values of each column of the imported data. newbook; wbook.dc.add("CSV"); wks.dc.source$=System.path.program$+"Samples\Batch Processing\T275K.csv"; ...
The study shows for the first time that DC-SCRIPT deficiency delays mammary gland morphogenesis in vivo and in vitro. These data define DC-SCRIPT as a novel modulator of mammary gland development. 展开 关键词: 3D culture DC-SCRIPT/Zfp366 Mammary gland morphogenesis Organoids ...