Darunavir/ritonavir is indicated in combination with other antiretroviral drugs for the treatment of HIV-1 infection in pre-treated adult patients. In hepatitis B or C co-infected patients, the virological response rate to darunavir/ritonavir appeared to be unaffected and, except for increased liver...
Hull MW, Montaner JS. Etravirine in combination with darunavir/ritonavir and optimized background regimen results in suppression of HIV replication in treatment-experienced patients. Expert Opinion on Pharmacotherapy . 2010; 11 (8):1433–1437.
Darunavir is used in combination with ritonavir (Norvir®) and other medicines for the treatment of the infection caused by the human immunodeficiency virus (HIV). HIV is the virus that causes acquired immune deficiency syndrome (AIDS). This medicine is given to patients who have already had ...
Individual risk management strategy and potential therapeutic options for the COVID-19 pandemic 5.4.2 Darunavir Darunavir is another anti-retroviral protease inhibitor that often uses in combination with other cytochrome P450 inhibitors, such as ritonavir or cobicistat, for the treatment of HIV infection...
Pharmacokinetics ofDarunavirin Fixed-Dose Combination with Cobicistat Compared with Coadministration ofDarunavirand Ritonavir as Single Agents in Healthy Volunteers Kakuda Thomas N*; Opsomer Magda; Timmers Maarten; Iterbeke Koen; Van de Casteele Tom; Hillewaert Vera; Petrovic Romana; Hoetelmans Richard...
for lorlatinib. The validated UPLC-MS/MS method was used to study drug interactions of atazanavir, darunavir, indinavir, and ritonavir with alectinib in rat plasma. We found atazanavir, darunavir, indinavir, and ritonavir significantly inhibited alectinib metabolism. When administered with atazanavir, ...
(2004). Structure activity study and pharmacokinetic analysis: D. L. N. G. Surlerauxet al., J. Med. Chem.48, 1813 (2005). Review of pharmacology and clinical experience: A. C. Shurtleff,Curr. Opin. Invest. Drugs5, 879-886 (2004). Clinical evaluation of combination with ritonavir: ...
combinations, an efavirenz-based combination and ritonavir-boosted darunavir-based combinations with respect to virological suppression (plasma HIV-1 RNA <50 ... PL Mccormack - 《Drugs》 被引量: 30发表: 2014年 Drug interactions between voriconazole, darunavir/ritonavir and tenofovir/emtricitabine in ...
et al. Dual antiretroviral therapy with tenofovir (TDF) and darunavir/ritonavir (DRV/RTV) in an HIV-1 positive patient: a case report, review, and meta-analysis of the literature on dual treatment strategies using protease inhibitors in combination with an NRTI. Infection 46, 599–605 (2018)...
Ritonavir-boosted atazanavir exposure is associated with an increased rate of renal stones compared with efavirenz, ritonavir-boosted lopinavir and ritonavir-boosted darunavir. AIDS 25, 1671–1673 (2011). CAS PubMed Google Scholar Jose, S. et al. Improved kidney function in patients who switch ...