from cancer.1 Darbepoetin alfa and epoetin alfa share the same native protein sequence, but the molecules have distinct glycosylation patterns, resulting in a three-times longer serum half-life and a modestly reduced erythropoietin receptor affinity for darbepoetin compared with its predecessor, epoetin...
OBJECTIVE: To review and compare the data concerning the clinical activity of epoetin alfa versus darbepoetin alfa when administered to patients with cancer who are experiencing treatment-related anemia. DATA SOURCES: English-language publications from the MEDLINE database (1990-June 2005), published ar...
Methods Electronic records from the Premier hospital database (2006Q1-2011Q1) were used to identify inpatients aged 鈮 18 years that had a diagnosis for cancer, received chemotherapy during hospitalization, and received epoetin alfa (EPO) or darbepoetin alfa (DARB). Exclusion criteria were: a ...
So far, three drugs have been approved for the treatment of anaemia in patients with malignancies (epoetin alfa, epoetin beta and darbepoetin alfa). New... Engert - 《Annals of Oncology Official Journal of the European Society for Medical Oncology》 被引量: 101发表: 2005年 Clinical and econo...
{BLACKWELL PUBLISHING}, title = {A cost-consequence analysis of darbepoetin alfa administered every 3 weeks (Q3W\\\_DA) compared to weekly epoetin alfa (QW\\\_EA) or epoetin beta (QW\\\_EB) in patients with chemotherapy-induced anemia (CIA): A retrospective study}, volume = {9}, year...
Macdougall IC, Gray SJ, Elston O, et al. Pharmacokinetics of novel erythropoicsis stimulating protein compared with epoetin alfa in dialysis patients. J Am Soc Nephrol 1999; 10: 2392–5. PubMedCASGoogle Scholar Bargman JM, Jones JE, Petro JM. The pharmacokinetics of intraperitoneal erythropoi...
Presents a study on the therapeutic interchange of darbepoetin alfa for epoetin alfa in a multi-institution health care system in the U.S. Problems arising from the use of erythropoiesis-stimulating proteins for the treatment of anemia associated with chronic kidney disease; Evaluation on the therape...
Cost-effectiveness modelling of epoetin alfa and darbepoetin alfa in the treatment of chemotherapy-related anaemia in Sweden.doi:10.1016/S1098-3015(10)72167-7J LiwingP NäsmanH KernellD. D. GagnonY WuElsevier Inc.Value in Health
Epoetin -alfa costs less than darbepoetin-alfa in hospitalised patients, and may provide hospitals with a better option for managing pharmacy expenses, according to the findings of a retrospective study conducted in the US. Researchers evaluated data for 92 467 inpatients with cancer or chronic kidne...
PCN25 REAL-WORLD EPOETIN ALFA (EPO) AND DARBEPOETIN ALFA (DARB) DOSING AND COST CONSIDERATIONS IN ELDERLY HOSPITAL INPATIENTS: RESULTS FROM A LARGE OBSERVATIONAL STUDY Author links open overlay panelM Duh, F Vekeman, RS Mckenzie, P Lefebvre, S Watson, S Mody, CT PiechShow more Add to ...