Daratumumab (DARA) is the biological name of an Immunoglobulin G1k human monoclonal antibody. DARA the first-in-class therapy targeting CD38 expressing- plasma cells (PC) and plasma blasts. It has been approved for the treatment of multiple myeloma. It is also being examined in the setting of...
Daratumumab is a human monoclonal antibody that targets CD38, a cell surface protein that is overexpressed on multiple myeloma (MM) cells. Preclinical studies have shown that daratumumab induces MM cell death through several mechanisms, including complement-dependent cytotoxicity (CDC), antibody-dependent...
Daratumumab: the first anti-CD38 monoclonal antibody for the treatment of multiple myelomaCyrille TouzeauBenjamin HébraudXavier Leleu
Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors. PMID: 21187443 An evaluation of subcutaneous daratumumab for the treatment of multiple myeloma. PMID: 32659139 Daratumumab monotherapy in patients with heavily pretreated relapse...
仅用于工业应用或科学研究,不可用于人类或动物的临床诊断或治疗,非药用. Daratumumab (anti-CD38) is a recombinant monoclonal antibody to CD38. Daratumumab is an investigational anti-cancer drug which is indicated for the treatment of adult patients with multiple myeloma. MW =145.4 kDa.售后...
Daratumumab is a human monoclonal antibody that targets CD38, a cell surface protein that is overexpressed on multiple myeloma (MM) cells. Preclinical studies have shown that daratumumab induces MM cell death through several mechanisms, including complement-dependent cytotoxicity (CDC), antibody-dependent...
中文同义词: DARATUMUMAB ( 达妥木单抗 ) 达妥木单抗 DARATUMUMAB单抗 英文名称:Daratumumab 英文同义词: Daratumumab Daratumumab - 20mg/ml in water Daratumumab 21.7mg/ml Daratumumab USP/EP/BP Research Grade Daratumumab(DHD80801) Anti-Human CD38, Human Antibody,myeloma,inhibit,tumor,antibody,cell,adhesion...
规格 1mg 5mg 清除 货号:MB2803大包装询价 描述 其他信息 相关文档 小工具 Daratumumab;达雷木单抗 产品简介: Daratumumab is a recombinant IgG1k monoclonal antibody that binds to CD38 and leads to cell apoptosis. Daratumumab was granted orphan drug designation for the treatment of multiple myeloma, diffuse...
参考文献：[1]. Ghose J, Viola D, et al. Daratumumab induces CD38 internalization and impairs myeloma cell adhesion. Oncoimmunology. 2018;7(10):e1486948. Published 2018 Jul 23.[2]. de Weers M, et al. Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of ...
Daratumumab (Anti-Human CD38) is the first-in-class human-specificanti-CD38monoclonal antibody (IgG1). Daratumumab has anti-multiple myeloma (MM) effect. Daratumumab impairs MM cell adhesion, which results in an increased sensitivity of MM to proteasome inhibition[1][2]. ...