Damage to the skin by repetitive washing. Contact Dermatitis 1995;32:225–232Grunewald, AM (1995) Damage to the skin by repetitive washing. Contact Dermatitis 32: pp. 225-232Grunewald AM, Gloor M, Gehring W, Kleesz P (1995) Damage to the skin by repetitive washing. Contact Dermat 32(4...
Protein integrity in living organisms is susceptible to nonenzymatic posttranslational modifications, such as oxidation, which occur under both physiological and pathological conditions1,2. Protein quality control systems, primarily involving the proteasomal and lysosomal pathways, facilitate the removal of mod...
Protein integrity in living organisms is susceptible to nonenzymatic posttranslational modifications, such as oxidation, which occur under both physiological and pathological conditions1,2. Protein quality control systems, primarily involving the proteasomal and lysosomal pathways, facilitate the removal of mod...
A more recent study indicated that telomerase assembly and recruitment are also regulated by ATM and ATR, which are two key proteins that play essential roles in the DNA damage response13. Due to their G-rich and repetitive nature, telomeres can adopt secondary structures known as G4s14. G4s...
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coli DNA Damage, Mutation, Function, and Phenotype Data from Overproduced DDPs, Related to Figures 1–4 and 6 Table S2. Human Homologs of E. coli DDP Network Proteins, Related to Figures 2 and 3 Table S3. Human DDPs or Candidate DDPs Overrepresented among Known and Predicted Cancer-...
How paternal exposure to ionizing radiation affects genetic inheritance and disease risk in the offspring has been a long-standing question in radiation biology. In humans, nearly 80% of transmitted mutations arise in the paternal germline1, but the tran
Human skin is composed of three layers, of which the dermis is composed of an extracellular matrix (ECM) comprising collagen, elastin, and other proteins. These proteins are reduced due to skin aging caused by intrinsic and extrinsic factors. Among various internal and external factors related to...
Since non-covalent binding is weaker, it allows the renewal of fluorogen molecules avoiding photobleaching. This technique also provides the fluorescence emission “on demand,” since it allows to switch the signal on and off, by washing out non-covalently associated fluorogens [82], as implemented...