Pradaxa (dabigatran) is ananticoagulantthat works by blocking the clotting proteinthrombin. Pradaxa is used to preventblood clotsfrom forming because of a certain irregular heart rhythm (atrial fibrillation). Preventing these blood clots helps to reduce the risk of astroke. What Are Side Effects of...
Conclusions Dabigatran, as compared with vitamin K antagonists, is associated with similar stent patency rates and complications among patients with Budd–Chiari syndrome post‐endovascular intervention.doi:10.1111/jgh.14843Sanchit SharmaDepartment of Gastroenterology All India Institute of Medical Sciences, ...
Dabigatran is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity. It has been approved in the European Union and the United States of America for the prevention of thrombosis after major orthopedic surgery. It has also been approved by the American Food and Drug Admin...
Dabigatran (BIBR 953), an oral anticoagulant, is a reversible, potent, competitive direct thrombin inhibitor (Ki=4.5 nM). Dabigatran (BIBR 953) also inhibits thrombin-induced platelet aggregation (IC50=10 nM). 体外研究 Dabigatran (BIBR 953) shows concentration-dependent anticoagulant effects in vari...
Dabigatran etexilate mesylate is an anticoagulant drug. Dabigatran demonstrated its efficacy for prophylaxis and treatment of thromboembolic event during orthopaedic surgery and curative treatment of hypercoagulability in atrial fibrillation. The present study deals with the development and...Pintu...
Warfarin is an anticoagulant used to prevent heart attacks, strokes, and blood clots. Learn about ... Reviews & ratings 8.1 / 10 56 Reviews View more WarningsDo not stop taking dabigatran without your doctor's advice. Stopping it suddenly can increase your risk of blood clots or stroke.Som...
The active metabolite of the prodrug dabigatran etexilate, it acts as an anticoagulant which is used for the prevention of stroke and systemic embolism. View all Biological Activity bibr 953 is a potent, reversible, and direct inhibitor of thrombin with ic50 value of 9.3nm [1].bibr 953 ...
Dabigatran Etexilate Mesylate (CAS 872728-81-9) is a compound used as an anticoagulant medication. It is an oral prodrug of dabigatran, which is a direct thrombin inhibitor. Dabigatran Etexilate Mesylate is indicated for the prevention of stroke and systemic embolism in patients with non-valvular ...
[Abstract] Dabigatran etexilate is a novel oral anticoagulant that exerts its acti on by directly inhibiting thr ombin .Phase Ⅲstudies f or p reventi on of p ri m ary venous thr omboe mbolis m (VTE )have comp leted .Further phase Ⅲstudies are ongoing,including those f or acute VTE...
The main limitation of the present investigation is that the clinical relevance of measuring dabigatran in serum samples remains to be validated by clinical outcomes in clinical studies. The time of blood sampling after the intake of the last dose of the anticoagulant plays an important role and ...