KIT 突变位点 基因序列 KIT D816V D816V是一种在急性髓细胞白血病(AML)中观察到的突变。这种变异与AML患者预后差和预后差有关。KIT D816V is a mutation observed in acute myeloid leukemia (AML). This variant has been linked to poorer prognosis and worse outcome in AML patients....
Conclusion: The KIT D816V mutation is consistently present in lesional skin in adults with SM. The low variation in mutation levels detected in lesional skin contrasts blood and bone marrow where mast cell (MC) progenitor and non-MC lineage involvement causes the mutation-positive cell fraction ...
February 2016,Vol 51,No2 C—KIT—D81 6V、NPM 1基 因突变在急性髓系 白血病 中的临床 意义 ★ 熊丽芳 ,李萍 ,张荣艳 (1、南昌大学第三附属医院血液科,南昌 330006;2、南昌大学第一附属医院血液科,南昌 330006) · 实验研 究· 摘要:目的 探讨 C—KIT—D816V、NPM1与AML患者临床特征、疗效及预后相关...
u h u a l i @163.c o m ㊂侵袭性系统性肥大细胞增生症伴K I T D 816V 突变1例并文献复习 吴春燕1,武智敏1,周春晓1,吴少玲2,顾华丽3 (青岛大学,山东青岛 266071 1 医学部; 2 附属医院血液内科; 3 附属医院急诊科)[摘要] 目的 探讨侵袭性系统性肥大细胞增生症伴K I T D 816V 突变的临床...
KITD816V was detected by PCR sequencing in 50 or 20% of patients with or without TET2 mutation (P=0.05), respectively. Multivariable analysis showed a significant association between the presence of TET2 mutation and monocytosis (P=0.0003) or female sex (P=0.05). The association with mono...
Mutation of KIT receptor tyrosine kinase at residue D816 results in ligand-independent constitutive kinase activity. This mutation occurs in most patients with mastocytosis, a myeloproliferative neoplasm, and is detected at lower frequencies in acute myeloid leukemia and in germ cell tumors. Other KIT...
AI-Edigene® c-KIT p.D816V Reference Standard Plus询价 产品描述 产品数据库 CBP10507 Format Genomic DNA Description This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This ...
摘要: Multilineage involvement of bone marrow (BM) hematopoiesis by the somatic KIT D816V mutation is present in a subset of adult indolent systemic mastocytosis (ISM) patients in associ... 查看全部>> 年份: 2016 收藏 引用 批量引用 报错 分享 全部...
Serum tryptase correlates with the KIT D816V mutation burden in adults with indolent systemic mastocytosis Systemic mastocytosis (SM) is characterized by the growth of neoplastic mast cells (MCs). Most adults with indolent SM carry the KIT D816V mutation. We rec... T Kristensen,S Broesby-Ol...
flt3-itd、c-kit-d816v、npm1基因突变与急性髓系白血病临床特征及预后相关性研究,预后不良,预后良好,人狂犬病的预后是,预后是什么意思,疾病预后,直肠癌预后,鼻咽癌预后,预后较好,胃癌预后 文档格式: .pdf 文档大小: 2.84M 文档页数: 50页 顶/踩数: ...