This paper reports an investigation of the conversion reaction of d- and dl-aminolactam into l-lysine using both cells of Crypt, laurentii and Achr. obae nov. sp. The optimum pH of the reaction was between 8.0 and 9.0, but most often near 8.0. An inhibitory effect of the substrates on...
摘要: Discusses the critical involvement of a carbamylated lysine in catalytic function of class D beta-lactamases, the resistance enzymes for beta-lactam antibiotics. Classes of beta-lactamases; Multiple mechanisms for resistance to antibiotics; Feature for the catalytic events of class D enzymes....
Metabolic engineering has become a rational alternative to classical strain improvement in optimisation of β-lactam production. In metabolic engineering d... Jette,Thykaer,and,... - 《Metabolic Engineering》 被引量: 158发表: 2003年 Localization of the lysine epsilon-aminotransferase (lat) and delta...
Manufacturing methodological null system I of N protective 3 pyro lysine - lactam substitutionA new process is disclosed for the preparation of bipyrrolidinyl compounds of formula Iwherein * signifies an asymmetric center with an (R) or (S) configuration and X represents chlorine, bromine or ...
Discusses the critical involvement of a carbamylated lysine in catalytic function of class D beta-lactamases, the resistance enzymes for beta-lactam antibiotics. Classes of beta-lactamases; Multiple mechanisms for resistance to antibiotics; Feature for the catalytic events of class D enzymes....
Production method of 2- oxo pyro lysine chemical compound(57)< Abstract > Production method of the lactam formula (i): < Conversion 1 >コルソンピエール-ジャンバビアックケヴィンエイコルテドナルドイープルジビラクレアエイシーニー...
A gene (lat) encoding lysine 6-aminotransferase was found upstream of the pcbAB (encoding alpha-aminoadipylcysteinyl-valine synthetase) and pcbC (encoding isopenicillin N synthase) genes in the cluster of early cephamycin biosynthetic genes in Nocardia lactamdurans. The lat gene was separated by ...
The novel benzo-fused lactam containing inhibitors of this invention include those of the formula (I) ##STR14## and ... DS Karanewsky - EP 被引量: 143发表: 1996年 Theoretical study on the proton shuttle mechanism of saccharopine dehydrogenase Saccharopine dehydrogenase (SDH) is the last ...
Useful other peptide spiro lactam, is the new peptide array which includes the peptide imitation thing unit of two rings or three rings with this invention. The peptide which is disclosed with this bill join to heart system normalizes the pressure of the showing and the heart after the ...
Importance of mixture of minor determinants and benzylpenicilloyl poly-l-lysine skin testing in the diagnosis of β-lactam allergy Comment in J Allergy Clin Immunol. 2006 Jan;117(1):220-1; author reply 221. J Allergy Clin Immunol. 2005 Nov;116(5):1167-8; author reply 1168-9. PJ Bousq...