D-(+)-半乳糖诱导呈现的重要特征:D-(+)-半乳糖常用来建立老化模型(Aging Model),这些模型常呈现一些标志性生理特征,包括寿命缩短,认知衰退,老年性耳聋(presbycusis),氧化应激增强,抗氧化酶活性降低,免疫应答减少,末端糖基化产物提高,线粒体突变DNA积累,和线粒体功能丧失等。
Due to cost and time constraints, a mimetic aging model is generally preferred to naturally aged animals to study the underlying mechanisms of aging liver. The use of D-galactose in aging research is dated back to 1962 and has since been used widely. This review aims to comprehensively ...
D-Galactose (Alpha-D-galactose) is a naturally occurring hexose sugar that combines with glucose to form lactose. D-Galactose is often used in animal aging models. 体外活性 长期暴露于D-Galactose 可在小鼠体内诱发神经退化,这一过程通过增强caspase介导的细胞凋亡、抑制神经发生和神经元迁移和增加氧化损伤...
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The journal of nutrition, health & aging - Age-related hearing loss (ARHL) is much more prevalent with age, affecting not only peripheral but central auditory system. We have previously...关键词: Aging model in vitro auditory cortical neurons mitochondrial oxidative stress apoptosis D-galactose ...
aging mice.Results Compared with model group,theanine significantly increased the learning and memory abilities of aging mice.It also increased the activities of SOD and AchE,decreased the amount of MDA(P0.05,P0.01).Conclusion Theanine has the anti-aging effects on aging model mice and its ...
Objective To investigate the effects of Pingmaitong granules on free radical metabolism of D-galactose-induced subacute aging model. 目的探讨平脉通颗粒对D-半乳糖所致亚急性衰老模型自由基代谢的影响。 www.dictall.com 5. Objective: To explore the effect of Cordyceps militaries on learning and memory ...
Aging is a major factor involved in neurological impairments, decreased anti-oxidant activities, and enhanced neuroinflammation. D-galactose (D-gal) has been considered an artificial aging model which induces oxidative stress and inflammatory response resulting in memory and synaptic dysfunction. Dietary ...
3) D_galactose induced mimetic aging D-半乳糖致拟衰老4) D-galactose sensecence model of rat D-半乳糖大鼠衰老模型5) D-galactose sensecence model D-半乳糖衰老模型 例句>> 6) D-galactose-induced senile mile D-半乳糖致衰小鼠 例句>> ...
2) D-galactose induced aging mice model D-半乳糖衰老模型鼠3) D-galactose-induced mice D-半乳糖模型小鼠 例句>> 4) D-galactose sensecence model of rat D-半乳糖大鼠衰老模型5) D-galactose sensecence model D-半乳糖衰老模型 例句>> ...