Evidence from one study suggests that this test may have less utility in older populations, but no empirical evidence was available to support an increase in the diagnostic threshold of interpretation of D-dimer results for those over the age of 65 years....
Close attention must be paid to the preanalytical (specimen collection and handling),[1] analytical (the testing process),[2] and postanalytical (test interpretation contribution to diagnosis and treatment)[3] variables associated with ... KJ Smock,RC Gosselin - 《Seminars in Thrombosis & Hemostas...
thus requiring additional confirmatory tests such asCTAor V/Q scan. D-dimer testing can produce a higher rate of false-positive results in certain populations, such as hospitalized patients, cancer patients, pregnant women, patients with renal dysfunction, and patients >50years of age[2...
The expert group compiled this consensus in order to solve the key problems faced by D-dimer in laboratory testing and provide a reference for the reasonable application and correct interpretation of D-dimer in clinical practice.二 Laboratory testing The use of monoclonal antibodies to recognize D-...
ProcedureRESULTSANDINTERPRETATION 1.OnlyremovetherequiredreagentsfromtheOncetheassayiscompleted,theresultsareautomatically refrigerator.Theycanbeusedimmediately.calculatedbythecomputerusingthecalibrationcurvethat 2.Useone“DEX2”stripandone“DEX2”SPR®fromtheisstoredbytheinstrument(4-parameterlogisticsmodel), ...
CYW, XY, TTW, and MFD aided in data interpretation and wrote the manuscript. All authors were involved in revising the article and approved the final version. Corresponding author Correspondence to Changyi Wang. Ethics declarations Competing interests The authors declare no competing interests. Ethical...
For the qualitative Clearview Simplify assay, no analyzer or calibration was needed, but interpretation of a test result was sometimes difficult because of poor color contrast. CONCLUSIONS: Point-of-care D-dimer assays show good and similar diagnostic accuracy. The quantitative Cardiac and Triage and...
Patients with inconclusive CTPA (technically inadequate for interpretation or isolated subsegmental PE) results underwent additional testing with compression ultrasonography, ventilation-perfusion lung scan, or pulmonary angiography. Given the uncertainty regarding the clinical relevance and optimal management of ...
INTERPRETATION AND CONCLUSIONS: This study shows that the new method can be included in prospective clinical trials to test the utility of D-dimer measurement in combination with other non-invasive diagnostic procedures in the management of DVT diagnosis....
Seventy seven cases were further excluded, 12 for loss of follow-up before 28 days and 65 were due to lack of D-dimer test results at admission. Finally, 115 patients were enrolled in the current study (Fig. 1). Baseline characteristics and clinical outcomes were shown in Table 1. ...