[69]SuzukiK, WadaH, ImaiH, et al. A re-evaluation of the D-dimer cut-off value for making a diagnosis according to the ISTH overt-DIC diagnostic criteria: communication from the SSC of the ISTH[J]. J Thromb Haemost, 2018, 16(7):1442-1444. DOI: 10.1111/jth.14134. [70]WuY, LuoL...
Unlike the FDA, the European Union (EU) on In Vitro Diagnostic Medical Devices Regulation does not specify study criteria for D-dimer assays to meet an exclusionary claim. Most manufacturers that market their assays in North America and the EU will comply with FDA regulations in order to meet...
多项研究应用YEARS算法(临床评估是否存在DVT的临床表现、咯血和高度疑似PE)结合D-二聚体的检测来排除妊娠期PE,若YEARS算法中各项均不符合,D-二聚体<1 000 ng/ml可排除PE;即使YEARS算法临床评估1项及1项以上符合,但D-二聚体<500 ng/ml也可排除 PE,使用YEARS算法结合D-二聚体可以减少影像学检查和辐射暴露[11...
The D-dimer test is frequently used with many different tools to calculate the probability of Pulmonary Embolism: for example the Revised Geneva Score or the Wells criteria (check the Pulmonary Embolism (PE) diagnosis section below). How to calculate D-dimer levels? In order to use the Age-...
对于主观PE发生率可能性较低的患者:若未达到全部8个PE排除标准(PE rule-out criteria,PERC),即年龄≥50岁、脉搏≥100/min、动脉氧饱和度<95%、单侧腿部肿胀、咯血、近期外伤或手术、既往PE或深静脉血栓形成史、外源性应用雌激素;...
Criteria for the safe use of D-dimer testing in emergency depart- ment patients with suspected pulmonary embolism: a multicenter US study. Ann Emerg Med 2002; 39: 144-152.Kline JA, Nelson RD, Jackson RE, Courtney DM. Criteria for the safe use of D-dimer testing in emergency department ...
Exclusion of these 197 unsafe patients significantly decreased the probability of PE in the remaining 737 (79.0%) safe patients to 13.3% (95% CI 10.9% to 15.9%).Simple clinical criteria can permit safe-dimer testing in the majority of ED patients with suspected PE. These criteria warrant ...
The Pulmonary Embolism Rule-out Criteria (PERC) score has shown excellent negative predictive value; however, its use in the European population with high prevalence of PE is controversial. In Europe, PERC is not part of routine practice. For low-risk patients, guidelines recommend D-dimer testin...
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