T-bet高表达且POLD1突变型亚组生存期最长,T-bet低表达且POLD1野生型亚组生存期最短,二组差异具有统计学意义(P=0.004,图6B);对IFN-γ亚组的预后分析显示:在EC样本中,IFN-y高表达且POLD1突变
Gasdermin D (GSDMD) is the common effector for cytokine secretion and pyroptosis downstream of inflammasome activation and was previously shown to form large transmembrane pores after cleavage by inflammatory caspases to generate the GSDMD N-terminal domain (GSDMD-NT)1,2,3,4,5,6,7,8,9,10. Her...
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项目简介:The research groups «CNS angiogenesis and neurovascular link» within the Neuroscience Center Zurich (University Zurich, University Hospital Zurich, and ETH Zurich), the «Laboratory for Exercise and Health» within the Department of Health Sciences and Technology (ETH Zurich), and the...
The Railway Recruitment Board (RRB), under the Ministry of Railways, aims to recruit 32,438 candidates under the 7th CPC Pay Matrix across different Railway Zones and Production Units (PUs). Applicants who have completed their 10th grade, ITI, or an equivalent qualification, or hold a National...
***Recruitment Drive***到指定地点接Candy和Mercedes回电影厂,追击并杀死阻止的人。 报酬:1000 ***Dildo Dodo***到指定地点驾驶海上飞机散发新电影海报。 先找到最远的一个蓝点,驾机穿越它,会出现一个红点,再穿越,则会出现下一个蓝点,依次在油耗尽前完成。 报酬:2000 ***Martha's Mug Shot***先驾驶骨架...
P.C.M. VAN DE KERKHOFDepartment of DermatologyBritish Journal of DermatologyM.G.J. BOKHOVEN , S. MARE , B.M. CZARNETZKI , P.E.J. ERP , J.B.M. BOEZEMAN , P.C.M. KERKHOF . (1988) Active vitamin D3 does not suppress recruitment of G0 cells following injury. British Journal ...
"By 2100, recruitment" — new births — "will be severely compromised or impossible everywhere except perhaps in the Queen Elizabeth Island subpopulation," in Canada's Arctic Archipelago, said Amstrup. 阿姆斯特拉普称,“到2100年,新生北极熊数量将会剧减甚至降为零,除了(加拿大北极群岛的)伊丽莎白女王群岛...
Here, we show that upon mRNA binding 4E-T represses translation and promotes deadenylation via the recruitment of the CCR4-NOT deadenylase complex. The interaction with CCR4-NOT is mediated by previously uncharacterized sites in the middle region of 4E-T. Importantly, mRNA decapping and decay ...
A total of 600 GBMSM were recruited by convenient sampling through outreaching in gay venues, online recruitment and peer referral. Participants completed a cross-sectional anonymous telephone interview. This study was based on a subsample of 580 GBMSM self-reported as HIV negative/unknown sero-sta...