2014. Environmental genotoxicity and cyto- toxicity in flounder (Platichthys flesus), herring (Clupea harengus) and Atlantic cod (Gadus morhua) from chemical muni- tions dumping zones in the southern Baltic Sea, Marine Environmental Research 96: 56-67. https://doi.org/10.1016/j.maren- vres....
If left unchecked genotoxicity can lead to inflammation, cell death, and even cancer (see section “Carcinogenicity”). Endogenous cytotoxic substances are a key feature of a healthy immune system. This too can be hijacked by environmental contaminants, increasing their abundance, and resulting in ...
Allium cepa test in environmental monitoring: a review on its application. Mutat Res. 2009;682:71–81. https://doi.org/10.1016/j.mrrev.2009.06.002. Article CAS Google Scholar Mangalampalli B, Dumala N, Grover P. Allium cepa root tip assay in assessment of toxicity of magnesium oxide ...
The results showed that the cytotoxicity and mutagenicity of PM larger than 1μm was significantly lower than PM sized 10nm–1μm. Furthermore, there was a noticeable trend that the smaller the size of the PM of sidestream cigarette smoke, the greater the toxicity...
a well-trained molecular biologist and a bioinformatic expert. This protocol can be applied both in cells and in vivo to identify highly expressed circRNAs affecting cell growth, either in unperturbed conditions or under environmental stimulation, without disturbing their cognate linear mRNAs. ...
MA Alawi,M Hourani,DA Hilal - 《Toxicological & Environmental Chemistry Reviews》 被引量: 21发表: 1995年 Profiling the toxicity of new drugs: A non animal-based approach integrating toxicodynamics and biokinetics Here we report the first measurements of polybrominated diphenyl ethers (PBDE 47, 99...
Some manufactured nanoparticles are metal-based and have a wide variety of applications in electronic, engineering and medicine. Until now, many studies have described the potential toxicity of NPs on pulmonary target, while little attention has been pai
The aim of this study was to evaluate the toxicity of rice bran supercritical CO2 extract (RB-SCE) in vitro and in vivo. A cytotoxicity assay revealed no inhibitory effects on cell viability in a mouse leukemic monocyte macrophage cell line (RAW 264.7) after 24-h incubation with 0.16 or 0....
Cytotoxic effect can be due to disruption of basal cellular mechanisms and cell integrity like cell morphology, cell viability, cell growth, metabolic rates and gene transcription controlling basal functions … (Afssa, 2006). Numerous cell responses to toxic stress occur before a measurable toxicity,...
However, investigating the impacts of AuNPs related to safety/toxicity in environmental and human health is crucial. Therefore, this chapter will generally describe the conventional (chemical and physical) and nonconventional (biogenic) synthesis of AuNPs, the main techniques applied to their ...