解析 细胞毒T淋巴细胞抗原-4(cytotoxic T lymphocyte antigen-4,CTLA-4)又称为CD152,为同源二聚体,表达于活化的T细胞上,其胞浆区可与磷酸酶(SHP-1、SHIP)结合,对T细胞具有负调节作用。它和CD28分子均能与CD80/CD86结合,共同调节免疫应答。 反馈 收藏 ...
Douroudis K, Prans E, Kisand K, Nemvalts V, Uibo R. Cytotoxic T- lymphocyte antigen 4 gene polymorphisms are associated with latent autoimmune diabetes in adults. Clinica Chimica Acta. 2009;403:226- 228.Cytotoxic T-lymphocyte antigen 4 gene polymorphisms are associated with latent autoimmune ...
CTLA-4全名为细胞毒T淋巴细胞相关抗原4(Cytotoxic T Lymphocyte-Associated Antigen-4,CTLA-4)又名CD152,是由CTLA-4基因编码的T细胞表面跨膜蛋白,其基因定位于2号染色体长臂3区3带(2q33),主要表达于活化的T淋巴细胞表面,与T细胞表面的协同刺激分子受体(CD28)在基因结构、染色体定位、序列的同源性及基因表达具有十分...
答案:细胞毒T淋巴细胞抗原-4(cytotoxic T lymphocyte antigen-4,CTLA-4)又称为CD15... 点击查看完整答案手机看题 你可能感兴趣的试题 名词解释 CD64 答案:CD64为FcγRⅠ,表达于单核细胞、巨噬细胞、树突状细胞。它是高亲和力的IgGFc受体,能与人的IgG1、... 点击查看完整答案手机看题 名词解释 淋巴细胞功...
van Gerven NM, de Boer YS, Zwiers A, et al. Cytotoxic T lymphocyte antigen-4 +49A/G polymor- phism does not affect susceptibility to autoimmune hepatitis. Liver Int 2013;33:1039-43.van Gerven NM, de Boer YS, Zwiers A, van Hoek B, van Erpecum KJ, Beuers U, et al. Cytotoxic...
antigen /ˈæntɪdʒən/ 释义n. 抗原 例句Antigen processing by macrophages precedes recognition of an antigen by lymphocytes.抗原被巨噬细胞加工表示该抗原将被淋巴细胞识别。 概述 概述 细胞毒性T淋巴细胞相关抗原-4(cytotoxic T-lymphocyte associated antigen-4, CTLA-4)是活化T细胞表面所表达...
Summary The negative role exerted by cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) in the regulation of T-cell activity, as induced by T-cell receptor (TCR)/CD3 and CD28 costimulation, has been widely described. In the present work we investigated the ...
To determine whether the functional A49G polymorphism of cytotoxic T-lymphocyte antigen-4 (CTLA-4), a T-cell surface molecule that modulates T-lymphocyte activation and influences the risk of developing alcohol-induced autoantibodies, plays a role in susceptibility to alcoholic liver disease (ALD) ...
variants also cytotoxic T lymphocyte : a T cell that usually bears CD8 molecular markers on its surface and that functions in cell-mediated immunity by destroying a cell (as a virus-infected cell) having a specific antigenic molecule on its surface ...
Polyclonal Antibody to Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) 供应商 Biomatik 产品货号 CAU26312 产品报价 ￥询价/100ul ￥询价/200ul 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868 ...