Action mechanismOsteoporosis is caused by unbalanced bone reconstruction processes which leads to areduction in bone mineral density and changes in bone microstructure,resulting in increased fracture risk.Osteoclasts are the only bone resorption cells in the body of human being,and are closely related ...
The mechanism of action of cytokines to control the release of hypothalamic and pituitary hormones in infection. Ann.N.Y.Acad.Sci. 2000; 917:4–18.:4–18 PubMed Google Scholar Chrousos, G.P. The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. N.Engl.J. Med. 1995;...
Onoguchi K, Yoneyama M, Takemura A, Akira S, Taniguchi T, Namiki H, et al. Viral infections activate types I and III interferon genes through a common mechanism. J Biol Chem. 2007;282(10):7576–81. ArticleCASPubMedGoogle Scholar Enk AH, Katz SI. Identification and induction of keratinoc...
Inflammatory cytokines within the central nervous system: sources, function, and mechanism of action 来自 NCBI 喜欢 0 阅读量: 59 作者: EN Benveniste 摘要: In recent years, there has been increasing evidence that soluble mediators such as cytokines from activated T lymphocytes and macrophages are ...
The putative role and mechanism of action of cytokines in the progression of arthritic diseases such as osteoarthritis (OA) has received particular attention because of the important interaction between articular cartilage and synovium i... JP Pelletier,PJ Roughley,JA Dibattista,... - 《Seminars in...
The mechanism of stress affecting brain, GI mucosa and GI permeability through inflammatory response system. Full size image Conclusion In conclusion, our results indicate that GI mucosal injury induced by FES is related to anemia. A correlation was found between GI mucosal injury/bleeding and the ...
The induction of these molecules in ischemic brain is time-locked and appears to be controlled in a highly regulated manner during the process of ischemic cascade. The functional role, interrelationship, and basic mechanism of action of these molecules are being increasingly recognized, while trials ...
Mechanism of Action and Physical Functions of TNF-α TNF-α plays a vital role in the upstream initiation stage of the inflammatory cascade response. It is a crucial cytokine in the Th1 signaling pathway. It can induce glial and vascular endothelial cells to express cell adhesion molecules (ICAM...
Spivak J. The mechanism of action of erythropoietin. Int J Cell Cloning 4:139–166, 1986. PubMedCASGoogle Scholar Dessypris EN, Krantz SB. Effects of pure erythropoietin on DNA-synthesis by human marrow day 15 erythroid burst forming units in short term liquid culture. Br J Haematol 56:295...
s, antivenoms, blood, blood components and plasma-derived products. Side effects of the currently approved cytokines in the CDER biologic product list [1] (as at June 2014) are reviewed here together with summaries of each product’s approved indications, properties and mechanism of action....