基于KEGG通路富集分析的薏苡仁不同成分对Cytokine-cytokine receptor interaction靶基因作用,目的:探讨薏苡仁不同组分对脾虚湿阻证大鼠细胞因子-细胞因子受体相互作用的影响及关键靶点。方法:以薏苡仁不同组分作用于脾虚湿阻证大鼠,通过其肠全基因表达谱测定,对筛选的差异基
GO、KEGG通路富集分析发现,三七可能主要通过人参皂苷Rh1、人参皂苷Rg1、月桂酸单甘油酯、β-胡萝卜苷(β-daucosterol)和人参环氧炔醇(panaxydol)等活性成分,作用于EGFR、STAT3、MAPK14、白介素-2(IL-2)等靶点,调节癌症信号通路(Pathways in cancer)、细胞...
疾病方面(Disease area):43个蛋白主要在自身免疫性疾病、免疫肿瘤、抗病毒效应、神经性炎症、代谢调节、组织修复等相关。 信号通路(Kegg pathway):43种蛋白广泛分布在多种通路中,其中Cytokine-cytokine receptor interaction通路有30种蛋白,JAK-STAT signaling pathway通路16种蛋白,IL-17 signaling pathway 15种蛋白,还和...
Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells.
趋化因子肿瘤坏死因子目的:探讨薏苡仁不同组分对脾虚湿阻证大鼠细胞因子-细胞因子受体相互作用的影响及关键靶点.方法:以薏苡仁不同组分作用于脾虚湿阻证大鼠,通过其肠全基因表达谱测定,对筛选的差异基因后进行KEGG分析,并对富集到的细胞因子-细胞因子受体相互作用通路基因进行主成分分析和Hierarchical Clustering聚类分析....
CCR5 (hsa:1234)属于如下哪些条pathway? (提示:搜索KEGG网站 http://www.genome.jp/kegg/) A.Cytokine-cytokine receptor interactionB.Chemokine signaling pathwayC.Wnt signaling pathwayD.p53 signaling pathway相关知识点: 试题来源: 解析 AB 反馈 收藏 ...
Enriched pathways across multiple databases (KEGG, ReactomeDB, Wikipathways) were linked to insulin receptor signalling, PI3K signalling cascade and Rho-GTPases (Fig. 2H). While each of these pathways are individually associated with diverse cellular functions, they are also remarkably interconnected....
ARTICLE Received 12 Jan 2015 | Accepted 16 Oct 2015 | Published 25 Nov 2015 DOI: 10.1038/ncomms9928 OPEN STAT5-regulated microRNA-193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling Nadine Haetscher1,2,*, Yonatan Feuermann1,3,*, Susanne Win...
Mycobacterium tuberculosis infection and invasion may be facilitated by herpes simplex virus 1 infection, endocytosis, and B cell receptor signaling pathways, as suggested by the potential roles of 6 key genes and 2 important miRNAs.Many people opt for home care as their preferred method for ...
The matrix-assisted laser evaporation (MAPLE) method guarantees the highest degree of interaction specificity when depositing ligands. The experiments' findings showcased S/N protein's binding to Hb and Mb, and RBD's binding to Hb. Significantly, they also indicated that chemically inactivated virus...