GO、KEGG通路富集分析发现,三七可能主要通过人参皂苷Rh1、人参皂苷Rg1、月桂酸单甘油酯、β-胡萝卜苷(β-daucosterol)和人参环氧炔醇(panaxydol)等活性成分,作用于EGFR、STAT3、MAPK14、白介素-2(IL-2)等靶点,调节癌症信号通路(Pathways in cancer)、细胞...
基于KEGG通路富集分析的薏苡仁不同成分对Cytokine-cytokine receptor interaction靶基因作用,目的:探讨薏苡仁不同组分对脾虚湿阻证大鼠细胞因子-细胞因子受体相互作用的影响及关键靶点。方法:以薏苡仁不同组分作用于脾虚湿阻证大鼠,通过其肠全基因表达谱测定,对筛选的差异基
Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells.
趋化因子肿瘤坏死因子目的:探讨薏苡仁不同组分对脾虚湿阻证大鼠细胞因子-细胞因子受体相互作用的影响及关键靶点.方法:以薏苡仁不同组分作用于脾虚湿阻证大鼠,通过其肠全基因表达谱测定,对筛选的差异基因后进行KEGG分析,并对富集到的细胞因子-细胞因子受体相互作用通路基因进行主成分分析和Hierarchical Clustering聚类分析....
Ⅲ大类的差异基因发挥了主要作用;KEGG分析显示,细胞因子-细胞因子受体相互作用差异基因主要涉及的信号通路出现在趋化因子家族和TNF家族中.结论:脾虚湿阻证大鼠细胞因子-细胞因子受体相互作用紊乱,薏苡仁各个组分,尤其是薏苡仁油能够很好的调理混乱的细胞因子体系,尤其是趋化因子,改善机体炎性反应及免疫功能,这可能是薏苡仁...
( figure 2 b). kegg pathway analysis revealed that decs were primarily involved in "cytokine‒cytokine receptor interaction," "mapk signaling pathway," "pi3k-akt signaling pathway," and "ras signaling pathway" ( figure 2 c). download: download high-res image (736kb) download: download full...
(KEGG, ReactomeDB, Wikipathways) were linked to insulin receptor signalling, PI3K signalling cascade and Rho-GTPases (Fig.2H). While each of these pathways are individually associated with diverse cellular functions, they are also remarkably interconnected. Activation of insulin receptors, along with...
信号通路(Kegg pathway):43种蛋白广泛分布在多种通路中,其中Cytokine-cytokine receptor interaction通路有30种蛋白,JAK-STAT signaling pathway通路16种蛋白,IL-17 signaling pathway 15种蛋白,还和Th17 cell differentiation、NOD-like receptor signaling pathway等通路相关。
信号通路(Kegg pathway):43种蛋白广泛分布在多种通路中,其中Cytokine-cytokine receptor interaction通路有30种蛋白,JAK-STAT signaling pathway通路16种蛋白,IL-17 signaling pathway 15种蛋白,还和Th17 cell differentiation、NOD-like receptor signaling pathway等通路相关。
百度试题 题目CCR5 (hsa:1234)属于如下哪些条pathway? (提示:搜索KEGG网站 http://www.genome.jp/kegg/) A.Cytokine-cytokine receptor interactionB.Chemokine signaling pathwayC.Wnt signaling pathwayD.p53 signaling pathway相关知识点: 试题来源: 解析 AB ...