Paiva B, Gutierrez NC, Rosinol L, et al. High-risk cytogenetics and persistent minimal residual disease by multiparameter flow cytometry predict unsustained complete response after autologous stem cell transplantation in multiple myeloma. Blood. 2011;119: 687-691....
Tam CS, Otero-Palacios J, Abruzzo LV, Jorgensen JL, Ferrajoli A, Wierda WG, et al. Chronic lymphocytic leukaemia CD20 expression is dependent on the genetic subtype: a study of quantitative flow cytometry and fluorescent in-situ hybridization in 510 patients. Br J Haematol. 2008;141(1):36...
Impact of pretransplantation minimal residual disease, as detected by multiparametric flow cytometry, on outcome of myeloablative hematopoietic cell transplantation for acute myeloid leukemia. J Clin Oncol 2011; 29: 1190–1197. Article Google Scholar Bartelink IH, Bredius RG, Ververs TT, Raphael MF...
Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry. Nat Biotechnol. 1998;16:743–7. Article CAS PubMed Google Scholar Martens UM, Zijlmans JM, Poon SS, Dragowska W, Yui J, Chavez EA, Ward RK, Lansdorp PM. Short telomeres on human chromosome 17p. Nat ...
Acute myeloid leukemia with MLL rearrangements: clinicobiological features, prognostic impact and value of flow cytometry in the detection of residual leukemic cells. Leukemia, 17 (2003), pp. 76-82 CrossrefView in ScopusGoogle Scholar 90 Barjesteh van Waalwijk van Doorn-Khosrovani S, Erpelinck ...
In addition to marrow morphology and flow cytometry, our institution performs cytogenetics (CG) and NGS‐based testing routinely in patients with suspected MDS. We evaluated the relative value of NGS in the assessment of patients with suspected MDS. We initially compared the diagnostic and ...
FLOW cytometryDIAGNOSISSummary: Next‐generation sequencing (NGS) increasingly influences diagnosis, prognosis and management of myelodysplastic syndrome (MDS). In addition to marrow morphology and flow cytometry, our institution performs cytogenetics (CG) and NGS‐based testing routinely in patients with ...
Flow cytometry may also be the unique method incorporating strong analytical utility to calculate the cell nucleus’s physical size and genome [95,96]. Flow cytometry is a comparatively simple and easy method of calculating a polyploid’s nuclear DNA material. By measuring the relative DNA content...
As full activation of Akt requires phosphorylation on both threonine 308 (Thr308) and serine 473 (Ser473) residues, we studied the level of phosphorylation on the both sites in 58 AML samples by flow cytometry. The ratio of the mean fluorescence intensity of Thr308 and Ser473 represented a ...
MRD is a high-sensitive measure of residual MM cells in bone marrow, which can currently be evaluated using with multicolor flow cytometry or NGS to detect MRD sensitively up to around 10–6of all bone marrow cells [101]. MRD-negativity is associated with improved survival outcomes in MM, ...