Yoshida Y (1988) Cytochrome P450 of fungi: primary target for azole antifungal agents. Cur Top Med Mycol 2:388-418.Yoshida, Y., 1988, Cytochrome P450 of fungi: primary target for azole antifungal agents, in : “Current topics in medical mycology”, Vol.2, M.R. McGinnis, ed., ...
Within the above concentration range, a significant dose-effect relationship also exi sted between degrading-PAHs ability and P450 content in the fungi. Among the f our fungi selected, the order of phenanthrene-degrading and pyrene-degradi ng ability was as follows: Zj1 Zj3 Zj2 and Zj4. ...
Cytochrome P450 monooxygenases (CYPs/P450s) are heme-thiolate proteins whose role as a drug target against pathogenic microbes has been explored because of their stereo- and regio-specific oxidation activity. We aimed to assess the CYP53 family's role as a common alternative drug target against ...
Improvement of Cytochrome-P450-Mediated Biotransformations by Filamentous FungiCytochrome P450 enzymes are found throughout nature and form a superfamily of enzymes with ca. 500 members identified to date. P450's are monooxygenases involved in conversion of substrates such as (poly)aromatic hydrocarbons,...
a敲打 Striking [translate] aCytochrome P450 (CYP} enzymes are heme-containing monooxygenases catalyzing diverse reactions in many bacteria and in all archaea, fungi, and higher eukaryotes.' 正在翻译,请等待... [translate] 英语翻译 日语翻译 韩语翻译 德语翻译 法语翻译 俄语翻译 阿拉伯语翻译 西班牙语...
Interestingly, the deletion mutants and SG138 show a reduction of growth rate on agar plates, which is more significant on minimal CD agar (Fig. 4C) than on CM (Fig. 4A). The similar characteristics for T20, T49 (data not shown), and SG138 as well as the described loss of P450-...
Cytochrome P450 (CYP} enzymes are heme-containing monooxygenases catalyzing diverse reactions in many bacteria and in all archaea, fungi, and higher eukaryotes.'问题补充:匿名 2013-05-23 12:21:38 细胞色素P450(CYP}酶是血红素含有单加氧酶催化在许多细菌,并在所有古细菌,真菌和高等真核生物的不同...
Marker-free deletion mutant ∆ikaD was screened by a diagnostic PCR and the removal of the whole ikaD was confirmed by DNA sequencing of the mutant gene locus in ∆ikaD. To com- plement the ikaD mutation, a plasmid pComikaD, in which the complete ikaD gene under the control ...
Mice with a floxed Cyp1a1 allele has also been generated, and used for tissue-specific deletion of Cyp1a1 in the liver or intestine (Shi et al., 2010). There are at least 13 variant CYP1A1 alleles (http://www.cypalleles.ki.se/; Sim and Ingelman-Sundberg, 2010). A number of ...
Phylogenetic analyses were performed using the neighbor-joining (NJ), minimum evolution (ME), and maximum-likelihood (ML) methods as implemented in MEGA version 5.05 with 1,000 bootstraps[68]. In order to deal with alignment gaps we used a pair-wise deletion method for NJ and ME trees, ...