The contents of this book are: Resonance Raman Spectroscopy of Metalloporphyrins; Vibrational Modes of Coordinated CO, CN, O/sub 2/, and NO; Heme Protein Structure and the Iron-Histidine Stretching Mode; Transient and Cryogenic Studies of Photodissociated Hemoglobin and Myoglobin; Cytochrome C; Cyt...
Cytochrome c biogenesis is an intricate process present in virtually all organisms, and ensures the covalent ligation of heme to an apocyt c (Fig. 1). It relies on major cellular functions such as protein translocation followed by post-translational modification, extra-cytoplasmic protein folding an...
Members of this family are known to transport small solutes or drugs, but so far, no MFS protein was implicated in cbb3–Cox biogenesis. In order to dissect the mechanism of Cu acquisition in the absence of CcoA, we isolated ΔccoA mutants that were cbb3–Cox defective after addition of...
2. Diversity of cytochrome c biogenesis systems Cytochrome c biogenesis is an intricate process present in virtually all organisms, and ensures the covalent ligation of heme to an apocyt c (Fig. 1). It relies on major cellular functions such as protein translocation followed by post-translational...
A Highlights from MBoC Selection: Role of mitochondrial inner membrane organizing system in protein biogenesis of the mitochondrial outer membrane The mitochondrial inner membrane organizing system (MINOS) is a large protein complex required for maintaining inner membrane architecture. We report that ......
F1F0 ATP synthase subunit c is a substrate of the novel YidC pathway for membrane protein biogenesis TheEscherichia coliYidC protein belongs to the Oxa1 family of membrane proteins that have been suggested to facilitate the insertion and assembly of membra... van der Laan,M. - 《Journal of...
The reported model of an Apaf-1/cytochromeccomplex provides insights in the nature of protein-protein interactions which are hard to observe in crystallographic or electron microscopy studies. Bifurcated salt bridges can be expected to be stronger than simple salt bridges, and their formation might ...
They found that levels of a key protein involved in maintaining mitochondrial function and energy metabolism, cytochrome c oxidase subunit 5a (Cox5a), were significantly decreased in heart cells during oxygen deprivation. Further, they identified two microRNAs that acted to inhibit Cox5a after a ...
Such motifs were found to be conserved in multiheme c-type cytochromes even when the corresponding primary sequences were not related. Conserved heme packing motifs might be a general feature of cytochromes of the NapC/NirT family. 4.2. Cytochrome c biogenesis in W. succinogenes Covalent ...
Cytochrome c oxidase of mammalian cells is a large multicomponent membrane protein of considerable structural complexity (molecular size 200 kDa). Two heme moieties (heme a and heme a3), two redox-active copper sites (Cua and Cub), one zinc, and one magnesium are the possible absorbing chromo...