Cytidine diphosphate diacylglycerol per se is rarely noticed in analyses of lipid compositions of tissues, as it is present is such small amounts, perhaps only 0.05% or so of the total phospholipids. Indeed, the composition of the fatty acids or molecular species in this lipid in nature (as ...
Cytidine diphosphate diacylglycerol (CDP-DAG), an important intermediate for glycerolipid biosynthesis, is synthesized under the catalytic activity of CDP-DAG synthase (CDS) to produce anionic phosphoglycerolipids such as phosphatidylglycerol (PG) and cardiolipin (CL). Previous studies showed that ...
Here, the PA encounters cytidine triphosphate (CTP) formed by various nucleotide kinases from cytidine (or uridine) and, catalyzed by cytidine diphosphate-diacylglycerol (CDP-DG) synthase (CDS), PA and CTP react to yield CDP-DG. PI synthase (PIS) then catalyzes CDP-DG reaction with myo-...
UDP+ATP⇌nucleoside diphosphate kinaseUDP+ADP Formation of Other Pyrimidine Nucleotides UMP is the parent compound in the synthesis of cytidine and deoxycytidine phosphates and thymidine nucleotides (which are deoxyribonucleotides). Synthesis of Cytidine Nucleotides CTP is synthesized from UTP by transfer...
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Lilley AC, Major L, Young S, Stark MJ, Smith TK. 2014. The essential roles of cytidine diphosphate-diacylglycerol synthase in bloodstream form Trypanosoma brucei. Mol Microbiol 92:453- 470. http://dx.doi.org/10 .1111/mmi.12553.Lilley, A. C., Major, L., Young, S., Stark, M. J....
Cytidinediphosphate‐diacylglycerol synthase 5 is required for phospholipid homeostasis and is negatively involved in hyperosmotic stress tolerancedoi:10.1111/tpj.13916Hong, YueYuan, ShuSun, LinxiaoWang, XueminHong, YueyunPlant Journal
Kleppinger-Sparace, K.F. and Moore, T.S. Jr ( 1985 ) Biosynthesis of cytidine 5'-diphosphate-diacylglycerol in endoplasmic reticulum and mitochondria of castor bean endosperm . Plant Physiol. , 77 , 12 – 15 .Klepp...
P.S. Uster, R.E. Pagano, Synthesis and properties of £uo- rescent analog of cytidine diphosphate-diacylglycerol and phosphatidylinositol, in: L. Freyz, H. Dreyfus, R. Massar- elli, S. Gatt (Eds.), Enzymes of Lipid Metabolism, vol. 2, Plenum, New York, 1986, pp. 493^500....
In addition, in cultured neural cells, growth in inositol-free, chemically defined medium is required to maximize the Li + -dependent CDP-diacylglycerol response. A major advantage of this method may be its ability to provide insight Into the regulation of phosphoinositide turnover since this ...