Cystine/GlutamateAntiporterBlockage InducesMyelinDegeneration FedericoN.Soria, 1 AlazneZabala, 1 OlatzPampliega, 1 AitorPalomino, 1 CristinaMiguelez, 2 LuisaUgedo, 2 HideyoSato, 3 CarlosMatute, 1 andMarıaDome
cystine-glutamate exchange transporter cystine-glutamate exchange transporter(cystine-glutamate exchange transporter) CAS: 化学式: 主页 产品 cystine-glutamate exchange transporter 中文名 cystine-glutamate exchange transporter 英文名 cystine-glutamate exchange transporter 英文别名 cystine-glutamate exchange ...
Glutamate transporter subtype 1 (GLT-1), cystine-glutamate exchanger (xCT) and glutamate/aspartate transporter (GLAST) are one of the key players in regulating extracellular glutamate concentration in the brain. Parenteral treatment with ceftriaxone, 尾-lactam antibiotic, has been reported to attenuate...
Targeting xCT, a cystine-glutamate transporter induces apoptosis and tumor regression for KSHV/HIV-associated lymphoma Back to article Negative-feedback loop between Nrf2/KEAP1 axis and xCT-GSH axis in PEL cells Go Yoshida, Tokyo Medical and Dental University 25 July 2014 The authors investigated...
The astrocytic cystine/glutamate antiporter system xc− represents an important source of extracellular glutamate in the central nervous system, with potential impact on excitatory neurotransmission. Yet, its function and importance in brain physiology
Measurements of the rate of uptake of cystine into the cells and the rate of release of glutamate from the cells indicate that the entry of cystine and the exodus of glutamate occur at a ratio close to 1:1. Since cystine is known to behave as an anionic form in this transport, it is...
We performed a genetic screen to identify factors responsible for glucose addiction and recovered the two subunits of the xCT antiporter (system xc−), which plays an antioxidant role by exporting glutamate for cystine. Disruption of the xCT antiporter greatly improves cell viability after glucose ...
cystine-glutamate exchange transporter structure CAS No. Chemical Name: cystine-glutamate exchange transporter Synonyms cystine-glutamate exchange transporter CBNumber: CB41399712 Molecular Formula: Molecular Weight: 0 MDL Number: MOL File: Mol file Request For Quotation...
[人 Cystine/glutamate transporter酶联免疫试剂盒检测原理]: 本实验采用双抗体夹心ELISA法。所提供的ELISA Kit是典型的夹心法酶联免疫吸附测定试剂盒(ELISA)。预先包被的抗体为抗人Cystine/glutamate transporter单克隆抗体。检测相抗体为多克隆抗体,经生物素(biotin)标记。样品和生物素标记抗体先后加入酶标板孔反应后,PB...
We have determined that the cystine/glutamate antiporter, solute carrier family 7 member 11 (SLC7A11; also known as xCT), is required for the reprogramming of chief cells into mucus-secreting metaplasia after parietal cell loss in the stomach. This study indicates that xCT is crucial for cystin...