Martin, X, Salas, M, Labeeuw, M, Pozet, N, Gelet, A, Dubernard, JM (1991) Cystine stones: the impact of new treatment. Br J Urol 68: pp. 239Martin, X, Salas, M, Labeeuw, M (1991) Cystine stones: the impact of new treatment. Br J Urol 68: pp. 234-9...
PURPOSE: To document the experiences of a single institution in evaluating the clinical courses and treatment outcomes of patients with cystine stones. MATERIALS AND METHODS: The clinical data of 14 patients with cystine stones who were treated at our institution from March 1994 to July 2012 were ...
Cystine Stones: The Impact of New Treatment The hardness and frequent recurrence of cystine stones present a special challenge to the urologist. In this study, 15 cystinuric patients (11 males, 4 fem... X Martin,M Salas,M Labeeuw,... - 《British Journal of Urology》 被引量: 65发表:...
Cystine stonesGlutathioneOxidative biomarkersOxidative stressThe present study evaluates and compares firstly the serum biomarkers of oxidative stress, superoxide dismutase (SOD), induced nitric oxide synthase (iNOS), malondialdehyde (MDA), glutathione oxidized...
Crystal growth inhibitors could be a novel treatment for patients with L-cystine kidney stones, according to a recent study published in Science.Although rare—affecting only around 20,000 patients in the USA—cystine stones tend to be larger than the more common calcium oxalate stones, and are...
Heterozygotes may excrete high levels of cystine, but rarely develop stones. Treatment in patients involves high fluid intake, and maintaining the urine pH above 7, because cystine is soluble at high pH. Cystine levels may also be controlled by sodium and protein restricted diet (Worcester and ...
We describe baseline metabolic abnormalities and evaluate mercaptopropionylglycine plus potassium citrate treatment for urinary abnormalities and to prevent new stone formation in children with cystine stones. Daily urinary excretions of calcium, oxalate, citrate, magnesium, urate and phosphorus were determine...
Noun1.cystine- a crystalline amino acid found in proteins (especially keratin); discovered in bladder stones amino acid,aminoalkanoic acid- organic compounds containing an amino group and a carboxylic acid group; "proteins are composed of various proportions of about 20 common amino acids" ...
It has been suggested recently that the first step in the formation of calcium oxalate stones appears to be crystallisation. This step is said to depend on the state of saturation of the urine. This hypothesis was checked in cystine stone formers. Cystine crystalluria was found in 83% of 24...
Summary Although they are two very distinct entities, uric acid and cystine stone disease share a common physico-chemical backgroud, i.e. urinary supersaturation with respect to a compound that is poorly soluble in an acid milieu. Therefore, high-fluid intake and urine alkalinization, preferably ...