Adult-specific gastrointestinal complications in those with cystic fibrosis are emerging, in particular biliary and gastrointestinal tract malignancies Novel therapies specifically targeting the defects in processing or function of the CFTR protein are available, providing opportunities to better understand diseas...
Opportunities for cystic fibrosis care teams to support treatment adherence. J Cyst Fibros. 2015;14(1):142-8.Riekert KA, Eakin MN, Bilderback A, Ridge AK, Marshall BC. Opportunities for cystic fibrosis care teams to support treatment adherence. J Cyst Fibros 2015;14:142-148....
Opportunities for the Use of Aerosolized α1-Antitrypsin for the Treatment of Cystic Fibrosis Allen ED. Opportunities for the use of aerosolized α 1 antitrypsin for the treatment of cystic fibrosis. Chest. 1996; 110 (Suppl):256S–60S. doi: ... ED Allen - 《Chest》 被引量: 34发表: ...
Cystic fibrosis (CF) is a genetic disorder that leads to formation of thick epithelial secretions in affected organs. Chronic microbial infections associated with thick mucus secretions are the hallmarks of lung disease in CF. Despite similar conditions
A cystic fibrosis drug targeting the basic defect that causes the condition has been shown to be safe and effective in newborns aged four weeks and above, new research involving RCSI University of Medicine and Health Sciences and Children's Health Ireland has found. ...
Long-term infection of the airways of cystic fibrosis patients with Pseudomonas aeruginosa is often accompanied by a reduction in bacterial growth rate. This reduction has been hypothesised to increase within-patient fitness and overall persistence of the pathogen. Here, we apply adaptive laboratory evo...
This report is independent research funded by the National Institute for Health Research (Research for Patient Benefit Programme, ‘A Prospective Pilot Study of Home Monitoring in Adults with Cystic Fibrosis (HOME-CF)’, PB-PG-0712-28104) and by an educational grant via the Gilead UK and Irelan...
Opportunities for cystic fibrosis care teams to support treatment adherence. J Cyst Fibros. 2015;14(1):142–148. doi:10.1016/j.jcf.2014.10.003 44. Jouet E, Flora LG, Las Vergnas O. Construction et reconnaissance des savoirs expérientiels des patients [Construction and recognition of patients...
Approximately 10% of Cystic Fibrosis (CF) patients, particularly those with CF transmembrane conductance regulator (CFTR) gene nonsense mutations, lack effective treatments. The potential of gene correction therapy through delivery of the CRISPR/Cas syst
J. Cystic fibrosis lung microbiome: opportunities to reconsider management of airway infection. Pediatr. Pulmonol. 50, S31–S38 (2015). PubMed Google Scholar Conrad, D. et al. Cystic fibrosis therapy: a community ecology perspective. Am. J. Respir. Cell. Mol. Biol. 48, 150–156 (2013)...