Cystic fibrosis could be a common life-bound autosomal recessive hereditary condition, with highest occurrence in Europe, North America, and Australia. The root of illness is mutation of a gene that encodes a chloride-conducting transmembrane channel known as the cystic fibrosis transmembrane ...
Cystic fibrosis: Molecular biology and therapeutic implications. (cover story) Discusses new information discovered about the gene structure, the mutational basis and the function of the protein in the cystic fibrosis (CF) gene. Chlor... Collins,S F. - 《Science》 被引量: 753发表: 1992年 ...
Book review: Cystic fibrosis. Lung Biology in Health Disease, Vol. 242."The search for truth is in one way hard and in another very easy. For it is evident that no-one can master it fully nor miss it wholly. But each adds a little to our knowledge of nature, and from all the ...
Cystic fibrosis is a fatal genetic disorder involving dysfunction of the cystic fibrosis transmembrane regulator protein (CFTR) resulting in progressive re... LW Velsor,C Kariya,R Kachadourian,... - 《American Journal of Respiratory Cell & Molecular Biology》 被引量: 175发表: 2006年 Cell prolife...
Use of model organisms and in vitro techniques relevant to developmental biology and medicine are acceptable, as are translational human studies.关键词:Cystic fibrosis of the Pancreas α -glucosidase glycogen lymphocytes lysosomes mitochondria DOI: 10.1203/00006450-197211000-00001 被引量: 50 ...
The cystic fibrosis transmembrane conductance regulator (CFTR) is a transmembrane protein that functions as an ion channel. Mutations in this protein cause Cystic Fibrosis. For this reason, it is important to study the structure and function of CFTR. In this study, constructs of CFTR (C-termini...
Pediatrics, Surfactant, and Cystic Fibrosis in AJRCCM 2003 To understand the molecular mechanisms of gonadal development and maturation in penaeid shrimp Marsupenaeus japonicus, eight differentially expressed genes... Tobin,J Martin - 《American Journal of Respiratory & Critical Care Medicine》 被引量: ...
Nature Reviews Molecular Cell Biology volume 7, pages 426–436 (2006)Cite this article 8211 Accesses 352 Citations 6 Altmetric Metrics details Key Points Cystic fibrosis transmembrane conductance regulator, (CFTR) is a member of the ATP-binding cassette (ABC) transporter superfamily. Mutations in ...
Chemistry and biology of the alginate of mucoid strains of pseudomonas aeruginosa in cystic fibrosis Author links open overlay panelNicholas J.RussellPeterGacesaShow more Share Cite https://doi.org/10.1016/0098-2997(88)90002-7Get rights and contentPrevious article in issue Next article in issue...
2Cystic Fibrosis Center, Verona, Italy; 3Istituto Clinico Humanitas IRCCS, Rozzano, Italy and 4Department of Translational Medicine, University of Milan, Milan, Italy Cystic fibrosis (CF) is a common life-threatening autosomal recessive disorder in the Caucasian population, and the gene responsible ...