Methods to classify bacterial pathogens in cystic fibrosis[J].{H}Methods in Molecular Biology 2011,742.Bjarnsholt T, Nielsen X, Johansen U, Norgaard L & Hoiby N (2011) Methods to classify bacterial pathogens in cystic fibrosis. Cystic Fibrosis: Diagnosis and Protocols, Vol. II: Methods and...
Cystic fibrosis (CF) is an autosomal recessive disorder that is common in individuals of European descent. It is caused by mutations in the CFTR gene, which encodes the CF transmembrane conductance...
Most deaths associated with cystic fibrosis result from progressive and end-stage lung disease. In individuals with cystic fibrosis, the lungs are normal in utero, at birth, and after birth, before the onset of infection and inflammation (except possibly for the presence of dilated submucosal gland...
Cystic fibrosis (CF), the most common life-shortening autosomal recessive disorder in populations of European origin, is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene on chromosome 7.1 The CFTR gene encodes a protein of 1480 aminoacid residues that functi...
A polymicrobial perspective of pulmonary infections exposes an enigmatic pathogen in cystic fibrosis patients. Lung disease is the leading cause of morbidity and mortality in cystic fibrosis (CF) patients. A modest number of bacterial pathogens have been correlated ... Christopher,D,Sibley,... - ...
Cystic fibrosis (CF) is a heterogeneous multiorgan disease caused by mutations in theCFTRgene leading to misfolding (and other defects) and consequent dysfunction of CFTR protein. The majority of mutations cause a severe CF phenotype, and people with this condition will require a wide variety of...
Cystic Fibrosis is a genetic disease characterized by inflammation in the airways, which leads to degeneration of the lung tissue. AI generated definition based on: Volatile Biomarkers, 2013 About this pageSet alert Also in subject areas: Biochemistry, Genetics and Molecular Biology Medicine and Denti...
bacterial pathogens such asNeisseria gonorrhoeae,Escherichia coli,Staphylococcus aureus,Listeria monocytogenes,Salmonella typhimuriumandPseudomonas aeruginosa. Ceramide and ceramide-enriched membrane platforms are also involved in the induction of apoptosis in infected cells, such as in epithelial and endothelial ...
Sodium Nitrite-Mediated Killing of the Major Cystic Fibrosis Pathogens Pseudomonas aeruginosa, Staphylococcus aureus, and Burkholderia cepacia under Anaero... A hallmark of airways in patients with cystic fibrosis (CF) is highly refractory, chronic infections by several opportunistic bacterial pathogens. A...
The interaction of pathogens with the epithelium causes S. aureus, and later P. aeuruginosa, to transform into a mucoid form which is much more difficult to eradicate with antibiotics, making them a significant part of the disease burden of cystic fibrosis. The main respiratory medications are ...